Sabine Bartnitzke
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Explore the profile of Sabine Bartnitzke including associated specialties, affiliations and a list of published articles.
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11
Citations
232
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Recent Articles
1.
Holzmann C, Markowski D, Bartnitzke S, Koczan D, Helmke B, Bullerdiek J
Mol Cytogenet
. 2015 Oct;
8:76.
PMID: 26468330
Mutations of mediator subcomplex 12 (MED12) and of high mobility group protein AT-hook 2 (HMGA2) are driver mutations in uterine leiomyomas (UL) that have not been observed to coexist in...
2.
Markowski D, Helmke B, Bartnitzke S, Loning T, Bullerdiek J
Int J Gynecol Pathol
. 2014 Oct;
33(6):568-72.
PMID: 25272295
Uterine fibroids rank among the most frequent symptomatic human tumors at all. Recent data suggest that mutations of the mediator subcomplex 12 gene (MED12) and rearrangements of the gene-encoding high-mobility...
3.
Markowski D, Tadayyon M, Bartnitzke S, Belge G, Helmke B, Bullerdiek J
Genes Chromosomes Cancer
. 2014 Jan;
53(4):317-23.
PMID: 24446130
Uterine leiomyomas (UL) are the most frequent symptomatic human tumors. Nevertheless, their molecular pathogenesis is not yet fully understood. To learn more about the biology of these common neoplasms and...
4.
Muller M, Drieschner N, Focken T, Bartnitzke S, Winter N, Klemke M, et al.
Anticancer Res
. 2013 Jul;
33(8):3069-78.
PMID: 23898062
Background: High-mobility group AT-hook 2 (HMGA2) protein acts as an oncofoetal transcriptional regulator. In mesenchymal tissues, its expression can be induced by a variety of growth factors such as fibroblast...
5.
Markowski D, Helmke B, Radtke A, Froeb J, Belge G, Bartnitzke S, et al.
BMC Womens Health
. 2012 Jan;
12:2.
PMID: 22233735
Background: Spontaneous cessation of growth is a frequent finding in uterine fibroids. Increasing evidence suggests an important role of cellular senescence in this growth control. Deciphering the underlying mechanisms of...
6.
Markowski D, Bartnitzke S, Loning T, Drieschner N, Helmke B, Bullerdiek J
Int J Cancer
. 2012 Jan;
131(7):1528-36.
PMID: 22223266
Recurrent chromosomal alterations are found in roughly 20% of all uterine fibroids but in the majority cytogenetic changes are lacking. Recently, mutations of the gene mediator subcomplex 12 (MED12) have...
7.
Markowski D, Helmke B, Belge G, Nimzyk R, Bartnitzke S, Deichert U, et al.
Anticancer Res
. 2011 Apr;
31(3):753-61.
PMID: 21498692
Aim: To address the influence of genes involved in stem cell self-renewal and senescence on the growth of leiomyoma cells in vitro and to explore possible therapeutic implications of a...
8.
Nezhad M, Drieschner N, Helms S, Meyer A, Tadayyon M, Klemke M, et al.
Cancer Genet Cytogenet
. 2010 Dec;
203(2):247-52.
PMID: 21156240
To quantify the expression of HMGA1 mRNA in uterine leiomyomas, the expression of HMGA1 was analyzed in a series including tumors with aberrations of chromosome 6 (n = 7) and...
9.
Markowski D, Bartnitzke S, Belge G, Drieschner N, Helmke B, Bullerdiek J
Cancer Genet Cytogenet
. 2010 Sep;
202(1):53-7.
PMID: 20804922
The in vitro growth of cells from uterine fibroids is characterized by an early onset of senescence. Often, an even lower growth potential than that of matching myometrial cells is...
10.
Klemke M, Meyer A, Nezhad M, Belge G, Bartnitzke S, Bullerdiek J
Cancer Genet Cytogenet
. 2010 Jan;
196(2):119-23.
PMID: 20082846
A subset of uterine leiomyomas (UL) shows chromosomal rearrangements of the region 12q14 approximately q15, leading to an overexpression of the high-mobility group protein A2 gene (HMGA2). Recent studies identified...