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Norbert Drieschner

Explore the profile of Norbert Drieschner including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 327
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Recent Articles
1.
Hofener H, Homeyer A, Forster M, Drieschner N, Schildhaus H, Hahn H
Comput Methods Programs Biomed . 2019 May; 173:77-85. PMID: 31046998
Background: Automated image analysis can make quantification of FISH signals in histological sections more efficient and reproducible. Current detection-based methods, however, often fail to accurately quantify densely clustered FISH signals....
2.
Muller M, Drieschner N, Focken T, Bartnitzke S, Winter N, Klemke M, et al.
Anticancer Res . 2013 Jul; 33(8):3069-78. PMID: 23898062
Background: High-mobility group AT-hook 2 (HMGA2) protein acts as an oncofoetal transcriptional regulator. In mesenchymal tissues, its expression can be induced by a variety of growth factors such as fibroblast...
3.
Eszlinger M, Krogdahl A, Munz S, Rehfeld C, Precht Jensen E, Ferraz C, et al.
Thyroid . 2013 Jul; 24(2):305-13. PMID: 23837487
Background: The diagnostic limitations of thyroid fine-needle aspiration (FNA), such as the indeterminate category, can be partially overcome by molecular analyses. However, until now, rearrangements have only been detected in...
4.
Rippe V, Flor I, Debler J, Drieschner N, Rommel B, Krause D, et al.
Mol Cytogenet . 2012 Oct; 5(1):40. PMID: 23062364
Chromosomal rearrangements of band 19q13.4 are frequent cytogenetic alterations in benign thyroid adenomas. Apparently, these alterations lead to the upregulation of genes encoding microRNAs of two clusters mapping to the...
5.
Sendt W, Rippe V, Flor I, Drieschner N, Bullerdiek J
Cancer Genet . 2012 Apr; 205(3):128-30. PMID: 22469512
Classical cytogenetic examination of a thyroid nodular goiter revealed the existence of two different cytogenetically aberrant cell clones. They were characterized by monosomy 13 as the sole abnormality in one...
6.
Markowski D, Bartnitzke S, Loning T, Drieschner N, Helmke B, Bullerdiek J
Int J Cancer . 2012 Jan; 131(7):1528-36. PMID: 22223266
Recurrent chromosomal alterations are found in roughly 20% of all uterine fibroids but in the majority cytogenetic changes are lacking. Recently, mutations of the gene mediator subcomplex 12 (MED12) have...
7.
Klemke M, Drieschner N, Belge G, Burchardt K, Junker K, Bullerdiek J
Genes Chromosomes Cancer . 2011 Dec; 51(4):402-8. PMID: 22179975
The t(2;3)(q13;p25) occurs in a subgroup of follicular-patterned thyroid tumors and leads to a fusion of the genes encoding for the thyroid-specific transcription factor paired box 8 (PAX8) and the...
8.
Kloth L, Belge G, Burchardt K, Loeschke S, Wosniok W, Fu X, et al.
BMC Clin Pathol . 2011 Nov; 11:13. PMID: 22050638
Background: Thyroid adenoma associated (THADA) has been identified as the target gene affected by chromosome 2p21 translocations in thyroid adenomas, but the role of THADA in the thyroid is still...
9.
Drieschner N, Rippe V, Laabs A, Dittberner L, Nimzyk R, Junker K, et al.
Cancer Genet . 2011 Aug; 204(7):366-74. PMID: 21872823
In benign thyroid lesions, three main cytogenetic subgroups, characterized by trisomy 7 or structural aberrations involving either chromosomal region 19q13.4 or 2p21, can be distinguished by conventional cytogenetics (CC). As...
10.
Klemke M, Drieschner N, Laabs A, Rippe V, Belge G, Bullerdiek J, et al.
Cancer Genet . 2011 Jul; 204(6):334-9. PMID: 21763631
The chromosomal translocation t(2;3)(q13;p25) characterizes a subgroup of tumors originating from the thyroid follicular epithelium and was initially discovered in a few cases of adenomas. Later, a fusion of the...