Dominique Nadine Markowski
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Explore the profile of Dominique Nadine Markowski including associated specialties, affiliations and a list of published articles.
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20
Citations
287
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Recent Articles
1.
Gunther K, Foraita R, Friemel J, Gunther F, Bullerdiek J, Nimzyk R, et al.
Cancer Epidemiol Biomarkers Prev
. 2016 Oct;
26(2):197-205.
PMID: 27742669
Background: The transcription factor high-mobility AT-hook 2 (HMGA2) is involved in stem cell renewal and is expressed in many tumor tissues. Head and neck squamous cell carcinomas (HNSCC) comprise tumors...
2.
Holzmann C, Markowski D, Von Leffern I, Loning T, Bullerdiek J
Anticancer Res
. 2015 Dec;
35(12):6445-56.
PMID: 26637855
Background/aim: Compared to leiomyomas, smooth muscle tumors of uncertain malignant potential (STUMP), and leiomyosarcomas (LMS) originating from the Muellerian duct are very rare. Their molecular pathogenesis remains poorly understood. The...
3.
Holzmann C, Markowski D, Bartnitzke S, Koczan D, Helmke B, Bullerdiek J
Mol Cytogenet
. 2015 Oct;
8:76.
PMID: 26468330
Mutations of mediator subcomplex 12 (MED12) and of high mobility group protein AT-hook 2 (HMGA2) are driver mutations in uterine leiomyomas (UL) that have not been observed to coexist in...
4.
Holzmann C, Markowski D, Koczan D, Kupker W, Helmke B, Bullerdiek J
Mol Cytogenet
. 2014 Dec;
7(1):88.
PMID: 25506394
Background: Recent findings on genetic changes in uterine leiomyomas suggest these benign tumors being a heterogeneous group of diseases in terms of molecular pathogenesis with those showing karyotype alterations as...
5.
Drosch M, Schmidt N, Markowski D, Zollner T, Koch M, Bullerdiek J
Mol Hum Reprod
. 2014 Mar;
20(7):664-76.
PMID: 24657878
Uterine fibroids are the most common gynecological tumors affecting women in their reproductive age. Despite this high incidence the pathogenesis of fibroids is widely unsolved. Whereas formerly only imbalances in...
6.
Holzmann C, Markowski D, Koczan D, Helmke B, Bullerdiek J
Mol Cytogenet
. 2014 Mar;
7(1):19.
PMID: 24593849
Background: Epitheloid leiomyoma is a rare subtype of benign smooth muscle tumors. Results: Herein, we present the results of classical cytogenetics, MED12 mutation analysis, and copy number variation array evaluation...
7.
Klemke M, Muller M, Wosniok W, Markowski D, Nimzyk R, Helmke B, et al.
PLoS One
. 2014 Feb;
9(2):e88126.
PMID: 24516594
In pleomorphic adenomas of the salivary glands (PASG) recurrent chromosomal rearrangements affecting either 8q12 or 12q14∼15 lead to an overexpression of the genes of the genuine transcription factor PLAG1 or...
8.
Markowski D, Tadayyon M, Bartnitzke S, Belge G, Helmke B, Bullerdiek J
Genes Chromosomes Cancer
. 2014 Jan;
53(4):317-23.
PMID: 24446130
Uterine leiomyomas (UL) are the most frequent symptomatic human tumors. Nevertheless, their molecular pathogenesis is not yet fully understood. To learn more about the biology of these common neoplasms and...
9.
Markowski D, Thies H, Gottlieb A, Wenk H, Wischnewsky M, Bullerdiek J
Genes Nutr
. 2013 Jul;
8(5):449-56.
PMID: 23881689
There is a clear link between overweight, gain of white adipose tissue, and diabetes type 2 (T2D). The molecular mechanism of the gain of adipose tissue is linked with the...
10.
Markowski D, Nimzyk R, Belge G, Loning T, Helmke B, Bullerdiek J
Mol Cytogenet
. 2013 Jun;
6(1):23.
PMID: 23738817
Background: Deletions of the gene encoding mediator subcomplex 12 (MED12) in human smooth muscle tumors rank among the most frequent genomic alterations in human tumors at all. In a minority...