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S van Delft

Explore the profile of S van Delft including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 910
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Recent Articles
1.
van Nieuw Amerongen G, van Delft S, Vermeer M, Collard J, van Hinsbergh V
Circ Res . 2000 Aug; 87(4):335-40. PMID: 10948069
Endothelial cells (ECs) actively regulate the extravasation of blood constituents. On stimulation by vasoactive agents and thrombin, ECs change their cytoskeletal architecture and small gaps are formed between neighboring cells....
2.
Gimond C, van der Flier A, van Delft S, Brakebusch C, Kuikman I, Collard J, et al.
J Cell Biol . 1999 Dec; 147(6):1325-40. PMID: 10601344
Adhesion receptors, which connect cells to each other and to the surrounding extracellular matrix (ECM), play a crucial role in the control of tissue structure and of morphogenesis. In this...
3.
Sander E, Klooster J, van Delft S, van der Kammen R, Collard J
J Cell Biol . 1999 Dec; 147(5):1009-22. PMID: 10579721
Using biochemical assays to determine the activation state of Rho-like GTPases, we show that the guanine nucleotide exchange factor Tiam1 functions as a specific activator of Rac but not Cdc42...
4.
van Leeuwen F, van Delft S, Kain H, van der Kammen R, Collard J
Nat Cell Biol . 1999 Nov; 1(4):242-8. PMID: 10559923
GTPases of the Rho family regulate actinomyosin-based contraction in non-muscle cells. Activation of Rho increases contractility, leading to cell rounding and neurite retraction in neuronal cell lines. Activation of Rac...
5.
Geijsen N, van Delft S, Raaijmakers J, Lammers J, Collard J, Koenderman L, et al.
Blood . 1999 Jul; 94(3):1121-30. PMID: 10419906
The small guanosine triphosphate (GTPase) p21rac is highly expressed in human neutrophils where it is thought to play a role in cytoskeletal reorganization and superoxide production. Using the p21rac binding...
6.
Whitehead B, Tessari M, Versteeg H, van Delft S, van Bergen en Henegouwen P, Vuister G
J Biomol NMR . 1998 Dec; 12(3):465-6. PMID: 9835057
No abstract available.
7.
Sander E, van Delft S, Klooster J, Reid T, van der Kammen R, Michiels F, et al.
J Cell Biol . 1998 Dec; 143(5):1385-98. PMID: 9832565
We previously demonstrated that both Tiam1, an activator of Rac, and constitutively active V12Rac promote E-cadherin-mediated cell-cell adhesion in epithelial Madin Darby canine kidney (MDCK) cells. Moreover, Tiam1 and V12Rac...
8.
van Delft S, Govers R, Strous G, Verkleij A, van Bergen en Henegouwen P
J Biol Chem . 1997 May; 272(22):14013-6. PMID: 9162018
Epidermal growth factor (EGF) receptor pathway substrate clone 15 (Eps15) has been described as a 142-kDa EGF receptor substrate. It has been shown to bind to the EGF receptor, adaptor...
9.
van Delft S, Schumacher C, HAGE W, Verkleij A, van Bergen en Henegouwen P
J Cell Biol . 1997 Feb; 136(4):811-21. PMID: 9049247
Eps15 has been identified as a substrate of the EGF receptor tyrosine kinase. In this report, we show that activation of the EGF receptor by either EGF or TGF-alpha results...
10.
van Delft S, Verkleij A, Boonstra J, van Bergen en Henegouwen P
FEBS Lett . 1995 Jan; 357(3):251-4. PMID: 7835422
Stimulation of cells by epidermal growth factor induces a rapid polymerisation of actin in the cortical skeleton. Activation of the EGF-receptor leads to autophosphorylation and to phosphorylation of specific intracellular...