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R A van der Kammen

Explore the profile of R A van der Kammen including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 1575
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Recent Articles
1.
Evers E, van der Kammen R, Klooster J, Collard J
Methods Enzymol . 2000 Oct; 325:403-15. PMID: 11036622
No abstract available.
2.
Michiels F, van der Kammen R, Janssen L, Nolan G, Collard J
Methods Enzymol . 2000 Oct; 325:295-302. PMID: 11036612
No abstract available.
3.
Evers E, Zondag G, Malliri A, PRICE L, Klooster J, van der Kammen R, et al.
Eur J Cancer . 2000 Jul; 36(10):1269-74. PMID: 10882865
Cell migration and the regulation of cadherin-mediated homotypic cell-cell interactions are critical events during development, morphogenesis and wound healing. Aberrations in signalling pathways involved in the regulation of cell migration...
4.
Zondag G, Evers E, Klooster J, Janssen L, van der Kammen R, Collard J
J Cell Biol . 2000 May; 149(4):775-82. PMID: 10811819
Proteins of the Rho family regulate cytoskeletal rearrangements in response to receptor stimulation and are involved in the establishment and maintenance of epithelial cell morphology. We recently showed that Rac...
5.
Sander E, Klooster J, van Delft S, van der Kammen R, Collard J
J Cell Biol . 1999 Dec; 147(5):1009-22. PMID: 10579721
Using biochemical assays to determine the activation state of Rho-like GTPases, we show that the guanine nucleotide exchange factor Tiam1 functions as a specific activator of Rac but not Cdc42...
6.
van Leeuwen F, van Delft S, Kain H, van der Kammen R, Collard J
Nat Cell Biol . 1999 Nov; 1(4):242-8. PMID: 10559923
GTPases of the Rho family regulate actinomyosin-based contraction in non-muscle cells. Activation of Rho increases contractility, leading to cell rounding and neurite retraction in neuronal cell lines. Activation of Rac...
7.
Sander E, van Delft S, Klooster J, Reid T, van der Kammen R, Michiels F, et al.
J Cell Biol . 1998 Dec; 143(5):1385-98. PMID: 9832565
We previously demonstrated that both Tiam1, an activator of Rac, and constitutively active V12Rac promote E-cadherin-mediated cell-cell adhesion in epithelial Madin Darby canine kidney (MDCK) cells. Moreover, Tiam1 and V12Rac...
8.
Stam J, Michiels F, van der Kammen R, Moolenaar W, Collard J
EMBO J . 1998 Jul; 17(14):4066-74. PMID: 9670021
Rho-like GTPases orchestrate distinct cytoskeletal changes in response to receptor stimulation. Invasion of T-lymphoma cells into a fibroblast monolayer is induced by Tiam1, an activator of the Rho-like GTPase Rac,...
9.
Hordijk P, Klooster J, van der Kammen R, Michiels F, Oomen L, Collard J
Science . 1997 Dec; 278(5342):1464-6. PMID: 9367959
Tiam1 encodes an exchange factor for the Rho-like guanosine triphosphatase Rac. Both Tiam1 and activated RacV12 promote invasiveness of T lymphoma cells. In epithelial Madin-Darby canine kidney (MDCK) cells, Tiam1...
10.
Stam J, Sander E, Michiels F, van Leeuwen F, Kain H, van der Kammen R, et al.
J Biol Chem . 1997 Nov; 272(45):28447-54. PMID: 9353304
The Rho-like GTPases Cdc42, Rac, and Rho play key roles in the regulation of the actin cytoskeleton and are implicated in transcriptional activation and cell transformation. We have previously identified...