S Pugazhenthi
Overview
Explore the profile of S Pugazhenthi including associated specialties, affiliations and a list of published articles.
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Articles
35
Citations
674
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Recent Articles
1.
Pugazhenthi S
Prog Mol Biol Transl Sci
. 2017 Mar;
146:243-258.
PMID: 28253987
Alzheimer's disease (AD) is characterized by cognitive dysfunction and progressive neurodegeneration. The major hallmarks of AD pathology are amyloid plaques and neurofibrillary tangles. However, AD often coexists with other brain...
2.
Gilden D, Mahalingam R, Nagel M, Pugazhenthi S, Cohrs R
Neuropathol Appl Neurobiol
. 2011 Feb;
37(5):441-63.
PMID: 21342215
Varicella zoster virus (VZV) is a neurotropic herpesvirus that infects nearly all humans. Primary infection usually causes chickenpox (varicella), after which virus becomes latent in cranial nerve ganglia, dorsal root...
3.
Loganathan G, Dawra R, Pugazhenthi S, Wiseman A, Sanders M, Saluja A, et al.
Transplant Proc
. 2010 Aug;
42(6):2055-7.
PMID: 20692406
Background: Exocrine tissue is commonly cotransplanted with islets in autografting and allotransplantation of impure preparations. Proteases and insulin are released by acinar cells and islets, respectively, during pretransplantation culture and...
4.
Pugazhenthi U, Velmurugan K, Tran A, Mahaffey G, Pugazhenthi S
Diabetologia
. 2010 Jul;
53(11):2357-68.
PMID: 20635178
Aims/hypothesis: Exendin-4, a glucagon-like peptide-1 (GLP-1) analogue, is reported to have modest anti-inflammatory effects in addition to that of improving beta cell survival. We therefore sought to determine whether exendin-4...
5.
Sarkar S, Kutlu B, Velmurugan K, Kizaka-Kondoh S, Lee C, Wong R, et al.
Diabetologia
. 2009 Apr;
52(6):1092-101.
PMID: 19343319
Aims/hypothesis: The destruction of pancreatic beta cells leading to type 1 diabetes in humans is thought to occur mainly through apoptosis and necrosis induced by activated macrophages and T cells,...
6.
Sarkar S, Gunter J, Bouchard R, Reusch J, Wiseman A, Gill R, et al.
Diabetologia
. 2007 Jun;
50(8):1649-59.
PMID: 17593347
Aims/hypothesis: Transplantation of islets is a viable option for the treatment of diabetes. A significant proportion of islets is lost during isolation, storage and after transplantation as a result of...
7.
Pugazhenthi S, Nesterova A, Sable C, Heidenreich K, Boxer L, Heasley L, et al.
J Biol Chem
. 2001 Feb;
275(15):10761-6.
PMID: 10753867
In our previous study we showed that insulin-like growth factor-I induces a cAMP-response element (CRE) site-containing Bcl-2 promoter through a novel signaling pathway involving mitogen-activated protein kinase kinase 6/p38beta mitogen-activated...
8.
Pugazhenthi S, Miller E, Sable C, Young P, Heidenreich K, Boxer L, et al.
J Biol Chem
. 1999 Sep;
274(39):27529-35.
PMID: 10488088
Insulin-like growth factor-I (IGF-I) is known to prevent apoptosis induced by diverse stimuli. The present study examined the effect of IGF-I on the promoter activity of bcl-2, a gene with...
9.
Pugazhenthi S, Boras T, OConnor D, Meintzer M, Heidenreich K, Reusch J
J Biol Chem
. 1999 Jan;
274(5):2829-37.
PMID: 9915817
IGF-I is known to support growth and to prevent apoptosis in neuronal cells. Activation of the nuclear transcription factor cAMP response element-binding protein (CREB) has emerged as a central determinant...
10.
Pugazhenthi S, Khandelwal R
Mol Cell Biochem
. 1998 Jun;
182(1-2):185-91.
PMID: 9609128
Effect of the antidiabetic agent pioglitazone on the insulin-mediated activation of protein phosphatase-1 was examined in diabetic hepatocytes. Streptozotocin-induced diabetes in Sprague Dawley rats caused a significant decrease in the...