S N Ho
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Explore the profile of S N Ho including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
5853
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Recent Articles
1.
Soria J, Ho S, Varella-Garcia M, Iafrate A, Solomon B, Shaw A, et al.
Ann Oncol
. 2018 Jul;
29(9):1964-1971.
PMID: 30010763
Background: In clinical trials of patients with anaplastic lymphoma kinase (ALK)-positive non-small-cell lung cancer (NSCLC) treated with crizotinib, evaluation of the relationship between the percentage of ALK-positive cells by fluorescence...
2.
Trama J, Lu Q, Hawley R, Ho S
J Immunol
. 2000 Oct;
165(9):4884-94.
PMID: 11046013
NFAT DNA binding complexes regulate programs of cellular activation and differentiation by translating receptor-dependent signaling events into specific transcriptional responses. NFAT proteins, originally defined as calcium/calcineurin-dependent regulators of cytokine gene...
3.
Redundant expression but selective utilization of nuclear factor of activated T cells family members
Timmerman L, Healy J, Ho S, Chen L, Goodnow C, Crabtree G
J Immunol
. 1997 Sep;
159(6):2735-40.
PMID: 9300694
Nuclear factor of activated T cells (NF-AT) complexes regulate the induction of many early T cell activation molecules. Four related proteins can function as the cytoplasmic subunit of NF-AT, and...
4.
FREIBERG R, Ho S, Khavari P
J Clin Invest
. 1997 Jun;
99(11):2610-5.
PMID: 9169490
The skin is an attractive tissue for regulated target gene expression by virtue of its accessibility to topical regulating stimuli. We have used synthetic ligand-driven intracellular oligomerization to accomplish specific...
5.
Beals C, Clipstone N, Ho S, Crabtree G
Genes Dev
. 1997 Apr;
11(7):824-34.
PMID: 9106655
The NF-AT family of transcription factors participates in the regulation of early immune response genes such as IL-2, IL-4, CD40 ligand, and Fas ligand in response to Ca2+/calcineurin signals initiated...
6.
Wolfe S, Zhou P, Dotsch V, Chen L, You A, Ho S, et al.
Nature
. 1997 Jan;
385(6612):172-6.
PMID: 8990122
Transcription factors of the NFAT family regulate the production of effector proteins that coordinate the immune response. The immunosuppressive drugs FK506 and cyclosporin A (CsA) act by blocking a Ca2+-mediated...
7.
Timmerman L, Clipstone N, Ho S, NORTHROP J, Crabtree G
Nature
. 1996 Oct;
383(6603):837-40.
PMID: 8893011
Cells need to distinguish between transient Ca2+ signals that induce events such as muscle contraction, secretion, adhesion and synaptic transmission, and sustained Ca2+ signals that are involved in cell proliferation...
8.
Ho S, Biggar S, Spencer D, Schreiber S, Crabtree G
Nature
. 1996 Aug;
382(6594):822-6.
PMID: 8752278
Eukaryotic transcriptional activators mediate transcriptional induction through stabilization of the preinitiation complex, probably through direct interactions with basal transcription factors. In vitro studies on the role of an activator in...
9.
Spencer D, Belshaw P, Chen L, Ho S, Randazzo F, Crabtree G, et al.
Curr Biol
. 1996 Jul;
6(7):839-47.
PMID: 8805308
Background: Genetic abnormalities in the Fas receptor or its trimeric ligand, FasL, result in massive T-cell proliferation and a lupus-like autoimmune syndrome, which was initially attributed to excessive lymphoproliferation but...
10.
Belshaw P, Ho S, Crabtree G, Schreiber S
Proc Natl Acad Sci U S A
. 1996 May;
93(10):4604-7.
PMID: 8643450
Extracellular growth and differentiation factors induce changes in gene expression in the nucleus by initiating a series of protein associations that alter the subcellular localization of intracellular signaling proteins. Initial...