S L Nutt
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Explore the profile of S L Nutt including associated specialties, affiliations and a list of published articles.
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26
Citations
1030
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Recent Articles
11.
Rolink A, Nutt S, Melchers F, Busslinger M
Nature
. 1999 Oct;
401(6753):603-6.
PMID: 10524629
The mechanisms controlling the commitment of haematopoietic progenitors to the B-lymphoid lineage are poorly understood. The observations that mice deficient in E2A and EBF lack B-lineage cells have implicated these...
12.
Nutt S, Heavey B, Rolink A, Busslinger M
Nature
. 1999 Oct;
401(6753):556-62.
PMID: 10524622
The Pax5 gene encoding the B-cell-specific activator protein (BSAP) is expressed within the haematopoietic system exclusively in the B-lymphoid lineage, where it is required in vivo for progression beyond the...
13.
Nutt S, Busslinger M
Biol Chem
. 1999 Aug;
380(6):601-11.
PMID: 10430025
It is generally assumed that most mammalian genes are transcribed from both alleles. Hence, the diploid state of the genome offers the advantage that a loss-of-function mutation in one allele...
14.
Nutt S, Vambrie S, Steinlein P, Kozmik Z, Rolink A, Weith A, et al.
Nat Genet
. 1999 Apr;
21(4):390-5.
PMID: 10192389
The developmental control genes of the Pax family are frequently associated with mouse mutants and human disease syndromes. The function of these transcription factors is sensitive to gene dosage, as...
15.
Thevenin C, Nutt S, Busslinger M
J Exp Med
. 1998 Aug;
188(4):735-44.
PMID: 9705955
The formation of the pre-B cell receptor (BCR) corresponds to an important checkpoint in B cell development that selects pro-B (pre-BI) cells expressing a functionally rearranged immunoglobulin mu (Igmu) heavy...
16.
Morrison A, Nutt S, Thevenin C, Rolink A, Busslinger M
Semin Immunol
. 1998 Jun;
10(2):133-42.
PMID: 9618759
Pax-5 codes for the transcription factor BSAP which is expressed throughout B cell development except in terminally differentiated plasma cells. Gene targeting experiments in the mouse revealed a differential dependency...
17.
Nutt S, Morrison A, Dorfler P, Rolink A, Busslinger M
EMBO J
. 1998 May;
17(8):2319-33.
PMID: 9545244
The Pax-5 gene codes for the transcription factor BSAP which is essential for the progression of adult B lymphopoiesis beyond an early progenitor (pre-BI) cell stage. Although several genes have...
18.
Nutt S, Thevenin C, Busslinger M
Immunobiology
. 1998 Jan;
198(1-3):227-35.
PMID: 9442394
Pax-5 codes for the transcription factor BSAP which is expressed in all B-lymphoid tissues in addition to the developing central nervous system and testis. Within the B-lymphoid lineage, Pax-5 expression...
19.
Nutt S, Urbanek P, Rolink A, Busslinger M
Genes Dev
. 1997 Feb;
11(4):476-91.
PMID: 9042861
The Pax5 gene coding for the transcription factor BSAP has an essential role in B lymphopoiesis and midbrain development. Here we present a detailed analysis of the B-cell phenotype of...
20.
Korczak B, Nutt S, Fletcher E, Hoo K, Elliott C, Rampersad V, et al.
Recept Channels
. 1995 Jan;
3(1):41-9.
PMID: 8589992
We have isolated a new member of the human glutamate receptor family from a fetal brain cDNA library. This cDNA clone, designated EAA3a, shares a 90% nucleotide identity with the...