K H Hoo
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Explore the profile of K H Hoo including associated specialties, affiliations and a list of published articles.
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8
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174
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Recent Articles
1.
Simmons R, Li D, Hoo K, Deverill M, Ornstein P, Iyengar S
Neuropharmacology
. 1998 Jul;
37(1):25-36.
PMID: 9680256
In order to study the roles of the AMPA and kainate subtypes of non-NMDA glutamate receptors in the processing of persistent nociceptive information, compounds with varying activities at these receptors...
2.
Clarke V, Ballyk B, Hoo K, Mandelzys A, Pellizzari A, Bath C, et al.
Nature
. 1997 Oct;
389(6651):599-603.
PMID: 9335499
The principal excitatory neurotransmitter in the vertebrate central nervous system, L-glutamate, acts on three classes of ionotripic glutamate receptors, named after the agonists AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxalole-4-propionic acid), NMDA (N-methyl-D-aspartate) and kainate....
3.
Cantrell B, Zimmerman D, Monn J, Kamboj R, Hoo K, Tizzano J, et al.
J Med Chem
. 1996 Sep;
39(19):3617-24.
PMID: 8809152
The synthesis and pharmacological characterization of a novel series of 4-aryl-substituted kainic acid analogs are described. Receptor affinities were determined on recombinantly expressed humGluR6 kainate receptors and on [3H]kainate binding...
4.
Korczak B, Nutt S, Fletcher E, Hoo K, Elliott C, Rampersad V, et al.
Recept Channels
. 1995 Jan;
3(1):41-9.
PMID: 8589992
We have isolated a new member of the human glutamate receptor family from a fetal brain cDNA library. This cDNA clone, designated EAA3a, shares a 90% nucleotide identity with the...
5.
Fletcher E, Nutt S, Hoo K, Elliott C, Korczak B, McWhinnie E, et al.
Recept Channels
. 1995 Jan;
3(1):21-31.
PMID: 8589990
A member of the ionotropic family of glutamate receptors, hGluR4, was isolated from a human cDNA library and characterized following expression in mammalian cell lines. Human GluR4 possessed a 99%...
6.
Hoo K, Kwan C, Daniel E
Can J Physiol Pharmacol
. 1994 Jan;
72(1):97-103.
PMID: 7912162
The ability of putative selective irreversible ligands SZL-49 (1-(4-amino-6,7-dimethoxy-2,5-diene-2-carbonyl)) and CEC (chlorethylclonidine), for alpha 1A and alpha 1B adrenoceptor subtypes, respectively, to affect alpha 1-adrenoceptors of canine aorta microsomal membranes...
7.
Nutt S, Hoo K, Rampersad V, Deverill R, Elliott C, Fletcher E, et al.
Recept Channels
. 1994 Jan;
2(4):315-26.
PMID: 7719709
Several cDNA clones encoding EAA5 receptor polypeptides were isolated from a human fetal brain library. The EAA5 cDNAs demonstrated an 88.7-90.1% nucleotide identity with rat GluR7 cDNAs. The nucleotide sequence...
8.
Hoo K, Nutt S, Fletcher E, Elliott C, Korczak B, Deverill R, et al.
Recept Channels
. 1994 Jan;
2(4):327-37.
PMID: 7536611
A cDNA encoding an ionotropic glutamate receptor subunit protein humEAA4 (GluR6), has been cloned from a human fetal brain library. This cDNA when expressed in COS or HEK-293 cells is...