S Karpatkin
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Explore the profile of S Karpatkin including associated specialties, affiliations and a list of published articles.
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Articles
185
Citations
2118
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Recent Articles
1.
Hypercoagulability preceding cancer. Does hypercoagulability awaken dormant tumor cells in the host?
Nierodzik M, Karpatkin S
J Thromb Haemost
. 2005 Mar;
3(3):577-80.
PMID: 15748252
No abstract available.
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Caunt M, Huang Y, Brooks P, Karpatkin S
J Thromb Haemost
. 2003 Oct;
1(10):2097-102.
PMID: 14521590
Most tumors have constitutively active tissue factor on their surface, capable of generating thrombin in the surrounding environment, and thrombosis is associated with cancer. Thrombin is known to induce a...
4.
Huang Y, Li J, Hu L, Lee M, Karpatkin S
Thromb Haemost
. 2001 Nov;
86(4):1094-8.
PMID: 11686329
Angiogenesis is required for tumor growth and metastasis. It has recently been suggested that thrombin is a potent promoter of angiogenesis. We therefore examined the possibility that thrombin could be...
5.
Nardi M, Tomlinson S, Greco M, Karpatkin S
Cell
. 2001 Sep;
106(5):551-61.
PMID: 11551503
Immunologic thrombocytopenia is seen commonly in HIV-1 infection. The pathogenesis of this problem has been unclear, but it is associated with circulating immune complexes that contain platelet membrane components and...
6.
Li J, Huang Y, Basch R, Karpatkin S
Thromb Haemost
. 2001 Mar;
85(2):204-6.
PMID: 11246533
Blood platelets contain angiopoietin-1, a growth factor essential for blood vessel development via stabilization of proliferating endothelial cells. It has recently been reported that angiopoietin-1 can act as a vascular...
7.
Nardi M, Karpatkin S
J Exp Med
. 2000 Jun;
191(12):2093-100.
PMID: 10859334
Patients with human immunodeficiency virus 1-associated immunological thrombocytopenia (HIV-1-ITP) have markedly elevated platelet-bound immunoglobulin (Ig)G, IgM, and C3C4, as well as serum circulating immune complexes (CICs) composed of the same....
8.
Zain J, Huang Y, Feng X, Nierodzik M, Li J, Karpatkin S
Blood
. 2000 May;
95(10):3133-8.
PMID: 10807779
Because thrombin-treated tumor cell-induced metastasis increases tumor nodule volume(12) greater than nodule number, we studied the effect of thrombin on tumor cell growth in vitro and in vivo (murine B16F10...
9.
Huang Y, Li J, Karpatkin S
Blood
. 2000 Mar;
95(6):1993-9.
PMID: 10706866
Angiopoietin-1 (Ang-1) is required for developing vessels, and its absence leads to defects in vessel remodeling. Ang-1 has been identified as the ligand for the tyrosine kinase receptor Tie-2, which...
10.
Huang Y, Li J, Karpatkin S
J Biol Chem
. 2000 Feb;
275(9):6462-8.
PMID: 10692450
Thrombin, a multifunctional protein, has been found to be involved in cellular mitogenesis, tumor growth, and metastasis, in addition to its well known effects on the initiation of platelet aggregation...