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S H Yuspa

Explore the profile of S H Yuspa including associated specialties, affiliations and a list of published articles. Areas
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Articles 293
Citations 5144
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Recent Articles
11.
Rehman I, Lowry D, Adams C, Abdel-Fattah R, Holly A, Yuspa S, et al.
Mol Carcinog . 2000 Apr; 27(4):298-307. PMID: 10747294
The skin tumor initiators N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) and 7,12-dimethylbenz[a]anthracene (DMBA) differ in effectiveness when tumor formation is promoted by 12-O-tetradecanoylphorbol-13-acetate (TPA). Even at high doses, MNNG is less effective, producing fewer...
12.
Fujii T, Garcia-Bermejo M, Bernabo J, Caamano J, Ohba M, Kuroki T, et al.
J Biol Chem . 2000 Mar; 275(11):7574-82. PMID: 10713064
Phorbol esters, the activators of protein kinase C (PKC), induce apoptosis in androgen-sensitive LNCaP prostate cancer cells. The role of individual PKC isozymes as mediators of this effect has not...
13.
Yuspa S
Carcinogenesis . 2000 Feb; 21(3):341-4. PMID: 10688853
In the foregoing articles, the editors of Carcinogenesis have identified the major themes of current carcinogenesis research and assembled an outstanding group of authors to review these areas. I have...
14.
Glick A, Popescu N, Alexander V, Ueno H, Bottinger E, Yuspa S
Proc Natl Acad Sci U S A . 1999 Dec; 96(26):14949-54. PMID: 10611318
Genetic inactivation of the transforming growth factor-beta (TGF-beta) signaling pathway can accelerate tumor progression in the mouse epidermal model of multistage carcinogenesis. By using an in vitro model of keratinocyte...
15.
Sagar M, Cheng C, Yuspa S, Weinberg W
J Biol Chem . 1999 Dec; 274(51):36488-97. PMID: 10593946
A novel chloride intracellular channel (CLIC) gene, clone mc3s5/mtCLIC, has been identified from differential display analysis of differentiating mouse keratinocytes from p53+/+ and p53-/- mice. The 4.2-kilobase pair cDNA contains...
16.
Li L, Lorenzo P, Bogi K, Blumberg P, Yuspa S
Mol Cell Biol . 1999 Nov; 19(12):8547-58. PMID: 10567579
Inactivation of protein kinase Cdelta (PKCdelta) is associated with resistance to terminal cell death in epidermal tumor cells, suggesting that activation of PKCdelta in normal epidermis may be a component...
17.
Diwan B, RIGGS C, LOGSDON D, Haines D, Olivero O, Rice J, et al.
Toxicol Appl Pharmacol . 1999 Nov; 161(1):82-99. PMID: 10558926
The anti-HIV drug 3'-azido-3'-deoxythymidine (AZT) is used successfully for reduction of perinatal viral transmission. However toxic side effects including carcinogenesis are possible. To test this, pregnant CD-1 Swiss mice were...
18.
Nesnow S, Cavanee W, Gilmer T, Kaufman D, Slaga T, Hohman R, et al.
Mol Carcinog . 1999 Jun; 25(2):99-106. PMID: 10365911
No abstract available.
19.
Bielenberg D, McCarty M, Bucana C, Yuspa S, Morgan D, Arbeit J, et al.
J Invest Dermatol . 1999 May; 112(5):802-9. PMID: 10233775
The cytokine interferon-beta is a regulator of cell replication and function, including invasion and induction of angiogenesis. The goal of this study was to determine whether the expression of interferon-beta...
20.
Weinberg W, Morgan D, Shalizi A, Mirosh E, Stanulis E, Deng C, et al.
Cancer Res . 1999 May; 59(9):2050-4. PMID: 10232585
Tumor suppression by p53 is believed to reside in its ability to regulate gene transcription, including up-regulation of p21WAF1. In p53(-/-) mice, chemical- or oncogene-induced skin tumors undergo accelerated malignant...