S H Gianturco
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Explore the profile of S H Gianturco including associated specialties, affiliations and a list of published articles.
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44
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566
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Recent Articles
1.
Datta G, Garber D, Chung B, Chaddha M, Dashti N, Bradley W, et al.
J Lipid Res
. 2001 May;
42(6):959-66.
PMID: 11369804
We previously showed 1 that a peptide, Ac-hE18A-NH(2), in which the arginine-rich heparin-binding domain of apolipoprotein E (apoE) [residues 141;-150] (LRKLRKRLLR), covalently linked to 18A (DWLKAFYDKVAEKLKEAF; a class A amphipathic...
2.
Brown M, Ramprasad M, Umeda P, Tanaka A, Kobayashi Y, Watanabe T, et al.
Proc Natl Acad Sci U S A
. 2000 Jun;
97(13):7488-93.
PMID: 10852956
We have cloned a human macrophage receptor that binds to apolipoprotein (apo)B48 of dietary triglyceride (TG)-rich lipoproteins. TG-rich lipoprotein uptake by the apoB48R rapidly converts macrophages and apoB48R-transfected Chinese hamster...
3.
Datta G, Chaddha M, Garber D, Chung B, Tytler E, Dashti N, et al.
Biochemistry
. 2000 Jan;
39(1):213-20.
PMID: 10625496
Human apolipoprotein E (apo E) consists of two distinct domains, the lipid-associating domain (residues 192-299) and the globular domain (residues 1-191) which contains the LDL receptor (LDLR) binding site (residues...
4.
Gianturco S, Bradley W
Clin Cardiol
. 1999 Jun;
22(6 Suppl):II7-14.
PMID: 10376191
Elevated plasma levels of triglyceride-rich lipoproteins (TGRLP), including very low-density lipoproteins (VLDL), chylomicrons, and their remnants, are now acknowledged as risk factors for cardiovascular disease. Interactions of TGRLP with lipoprotein...
5.
Bradley W, Brown M, Ramprasad M, Li R, Song R, Gianturco S
J Lipid Res
. 1999 Apr;
40(4):744-52.
PMID: 10191299
Two human monocyte-macrophage (HMM) membrane binding proteins, (MBP) 200 and 235, are receptor candidates that bind to the apolipoprotein (apo)B-48 domain in triglyceride-rich lipoproteins for uptake independent of apoE. Microsequence...
6.
Gianturco S, Ramprasad M, Song R, Li R, Brown M, Bradley W
Arterioscler Thromb Vasc Biol
. 1998 Jun;
18(6):968-76.
PMID: 9633939
Studies in animals and humans have demonstrated uptake of plasma chylomicrons (triglyceride-rich lipoprotein [TGRLP] of Sf>400) by accessible macrophages in vivo. One potential mechanism is via a unique receptor pathway...
7.
Li X, Grenett H, Benza R, Demissie S, Brown S, Tabengwa E, et al.
Arterioscler Thromb Vasc Biol
. 1997 Dec;
17(11):3215-23.
PMID: 9409314
The hypothesized relationships between plasminogen activator inhibitor (PAI-1) genotypes, PAI-1 levels, and their potential regulation by hypertriglyceridemic (HTG) very low density lipoprotein (VLDL) and lipoprotein(a) [Lp(a)] was examined in a...
8.
Li X, Koons J, Benza R, Parks J, Varma V, Bradley W, et al.
Biochemistry
. 1996 May;
35(19):6080-8.
PMID: 8634250
The effect of normo (NTG)- and hypertriglyceridemic (HTG)-VLDL on cultured human umbilical vein endothelial cell (HUVEC) surface-localized fibrinolysis was examined following pre-incubation with NTG-, HTG-VLDL, LDL (1-20 micrograms/mL) or buffer...
9.
Ramprasad M, Li R, Bradley W, Gianturco S
Biochemistry
. 1995 Jul;
34(28):9126-35.
PMID: 7619811
An apolipoprotein (apo) E- and lipoprotein lipase-independent, high affinity, saturable and specific binding site and pathway for uptake of certain triglyceride-rich lipoproteins (TGRLP) by human monocyte-macrophages that leads to lipid...
10.
Ramprasad M, Li R, Gianturco S, Bradley W
Biochem Biophys Res Commun
. 1995 May;
210(2):491-7.
PMID: 7755626
Previously we reported that human blood-borne and THP-1 monocyte-macrophages have an apolipoprotein E- and lipoprotein lipase-independent, high affinity, specific binding site for the uptake and degradation of hypertriglyceridemic VLDL and...