S F Stinson
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Explore the profile of S F Stinson including associated specialties, affiliations and a list of published articles.
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48
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Recent Articles
1.
Panasci L, Stinson S, Melnychuk D, Sandor V, Miller Jr W, Batist G, et al.
J Clin Oncol
. 2003 Jan;
21(2):232-40.
PMID: 12525514
Purpose: 2-Chloroethyl-3-sarcosinamide-1-nitrosourea (SarCNU) is a novel chloroethylnitrosourea that demonstrates selective cytotoxicity in athymic mice bearing human glioma. SarCNU demonstrates selective cytotoxicity in vitro against human glioma at least in part...
2.
Stinson S, House T, Bramhall C, Saavedra J, Keefer L, Nims R
Xenobiotica
. 2002 May;
32(4):339-47.
PMID: 12028666
1. The single-dose plasma pharmacokinetics of O(2)-vinyl 1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate (V-PYRRO/NO) following intravenous (i.v.) and intraperitoneal (i.p.) bolus administration to the male C57BL/6 mouse was studied in an effort to characterize the...
3.
Chua M, Kashiyama E, Bradshaw T, Stinson S, Brantley E, Sausville E, et al.
Cancer Res
. 2000 Oct;
60(18):5196-203.
PMID: 11016648
2-(4-Amino-3-methylphenyl)benzothiazole (DF 203, NSC 674495) is a candidate antitumor agent with potent and selective activity against human-derived tumor cell lines in vitro and in vivo. Only sensitive cell lines (e.g.,...
4.
Phillips L, Bramhall C, Buckley J, Wolfe T, House T, Stinson S
J Chromatogr B Biomed Sci Appl
. 2000 Jun;
741(2):205-11.
PMID: 10872590
During the course of our study to develop analytical methodology for quantitating the investigative antitumor agent 5-amino-2-(4-amino-3-fluorophenyl)-6,8-difluoro-7-methyl-4H-1-benzopyran -4-one (DAF; NSC 686288) in plasma, a significant concentration of a metabolite was...
5.
Phillips L, Bramhall C, Buckley J, Daw T, Stinson S
J Chromatogr B Biomed Sci Appl
. 1999 Oct;
732(2):315-21.
PMID: 10517353
Certain naturally occurring isoflavonoids have been shown to inhibit protein-tyrosine kinases, and this has led to investigations of ring-modified structural analogs. Most recently, 2-(3-methyl-4-aminophenyl)-benzothiazole (MAB: NSC 674495) was shown to...
6.
Kashiyama E, Hutchinson I, Chua M, Stinson S, Phillips L, Kaur G, et al.
J Med Chem
. 1999 Oct;
42(20):4172-84.
PMID: 10514287
2-(4-Aminophenyl)benzothiazoles 1 and their N-acetylated forms have been converted to C- and N-hydroxylated derivatives to investigate the role of metabolic oxidation in the mode of action of this series of...
7.
Schnier J, Kaur G, Kaiser A, Stinson S, Sausville E, Gardner J, et al.
FEBS Lett
. 1999 Jul;
454(1-2):100-4.
PMID: 10413104
The synthetic flavone flavopiridol can be cytostatic or cytotoxic to mammalian cells, depending on the concentration of the drug and the duration of exposure. It has been shown to inhibit...
8.
Rivera M, Stinson S, Vistica D, Jorden J, Kenney S, Sausville E
Biochem Pharmacol
. 1999 May;
57(11):1283-95.
PMID: 10230772
The tricyclic compound 2,5-bis(5-hydroxymethyl-2-thienyl)furan (NSC 652287) has shown a highly selective pattern of differential cytotoxic activity in the tumor cell lines comprising the National Cancer Institute (NCI) Anticancer Drug Screen....
9.
Randad R, Lubkowska L, Eissenstat M, Gulnik S, Yu B, Bhat T, et al.
Bioorg Med Chem Lett
. 1999 Feb;
8(24):3537-42.
PMID: 9934467
A series of novel unsymmetrical anthranilamide-containing HIV protease inhibitors was designed. The structure-activity studies revealed a series of potent P2-P3' inhibitors that incorporate an anthranilamide group at the P2' position....
10.
Stinson S, Hill K, Siford T, Phillips L, Daw T
Cancer Chemother Pharmacol
. 1998 Sep;
42(4):261-5.
PMID: 9744769
Purpose: Flavopiridol is a flavone which inhibits several cyclin-dependent kinases, and exhibits potent growth-inhibitory activity against a number of human tumor cell lines both in vitro, and when grown as...