S F Altschul
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Explore the profile of S F Altschul including associated specialties, affiliations and a list of published articles.
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36
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Recent Articles
1.
Schaffer A, Aravind L, Madden T, Shavirin S, Spouge J, Wolf Y, et al.
Nucleic Acids Res
. 2001 Jul;
29(14):2994-3005.
PMID: 11452024
PSI-BLAST is an iterative program to search a database for proteins with distant similarity to a query sequence. We investigated over a dozen modifications to the methods used in PSI-BLAST,...
2.
Altschul S, Bundschuh R, Olsen R, Hwa T
Nucleic Acids Res
. 2001 Jan;
29(2):351-61.
PMID: 11139604
The distribution of optimal local alignment scores of random sequences plays a vital role in evaluating the statistical significance of sequence alignments. These scores can be well described by an...
3.
Lash A, Tolstoshev C, Wagner L, Schuler G, Strausberg R, Riggins G, et al.
Genome Res
. 2000 Jul;
10(7):1051-60.
PMID: 10899154
We have constructed a public gene expression data repository and online data access and analysis, WWW and FTP sites for serial analysis of gene expression (SAGE) data. The WWW and...
4.
Schaffer A, Wolf Y, Ponting C, Koonin E, Aravind L, Altschul S
Bioinformatics
. 2000 Apr;
15(12):1000-11.
PMID: 10745990
Motivation: Many studies have shown that database searches using position-specific score matrices (PSSMs) or profiles as queries are more effective at identifying distant protein relationships than are searches that use...
5.
Lal A, Lash A, Altschul S, Velculescu V, Zhang L, McLendon R, et al.
Cancer Res
. 1999 Dec;
59(21):5403-7.
PMID: 10554005
A public database, SAGEmap, was created as a component of the Cancer Genome Anatomy Project to provide a central location for depositing, retrieving, and analyzing human gene expression data. This...
6.
Altschul S, Koonin E
Trends Biochem Sci
. 1998 Dec;
23(11):444-7.
PMID: 9852764
No abstract available.
7.
Chen H, Centola M, Altschul S, Metzger H
J Exp Med
. 1998 Nov;
188(9):1657-68.
PMID: 9802978
To characterize gene expression in activated mast cells more comprehensively than heretofore, we surveyed the changes in genetic transcripts by the method of serial analysis of gene expression in the...
8.
Zhang Z, Schaffer A, Miller W, Madden T, Lipman D, Koonin E, et al.
Nucleic Acids Res
. 1998 Aug;
26(17):3986-90.
PMID: 9705509
Protein families often are characterized by conserved sequence patterns or motifs. A researcher frequently wishes to evaluate the significance of a specific pattern within a protein, or to exploit knowledge...
9.
Altschul S
Proteins
. 1998 Jul;
32(1):88-96.
PMID: 9672045
Based on the observation that a single mutational event can delete or insert multiple residues, affine gap costs for sequence alignment charge a penalty for the existence of a gap,...
10.
Altschul S, Madden T, Schaffer A, Zhang J, Zhang Z, Miller W, et al.
Nucleic Acids Res
. 1997 Sep;
25(17):3389-402.
PMID: 9254694
The BLAST programs are widely used tools for searching protein and DNA databases for sequence similarities. For protein comparisons, a variety of definitional, algorithmic and statistical refinements described here permits...