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S E Wilkinson

Explore the profile of S E Wilkinson including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 570
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Recent Articles
1.
Wilkinson S, Nixon J
Cell Mol Life Sci . 1998 Nov; 54(10):1122-44. PMID: 9817991
The T lymphocyte has a vital part to play in maintaining the host response to bacterial and viral infection and also appears to play a key pathological role in autoimmune...
2.
Williams D, Wilkinson S, Purton T, Lamont A, Flotow H, Murray E
Biochemistry . 1998 Jul; 37(26):9579-85. PMID: 9649341
By using high throughput screening of microbial broths, we have identified a compound, designated Ro 09-2210, which is able to block anti-CD3 induced peripheral blood T cell activation with an...
3.
Merritt J, Sullivan J, Tse J, Wilkinson S, Nixon J
Cell Signal . 1997 Jan; 9(1):53-7. PMID: 9067630
Previous studies implicating a role for protein kinase C (PKC) in mediating stimulation of cellular responses by physiological agonists have relied on use of non-specific inhibitors or direct stimulation of...
4.
Bubeck Wardenburg J, Fu C, Jackman J, Flotow H, Wilkinson S, Williams D, et al.
J Biol Chem . 1996 Aug; 271(33):19641-4. PMID: 8702662
Two families of tyrosine kinases, the Src and Syk families, are required for T-cell receptor activation. While the Src kinases are responsible for phosphorylation of receptor-encoded signaling motifs and for...
5.
Flotow H, Purton T, Whitaker D, Williams D, Wilkinson S
Inflamm Res . 1996 Aug; 45(8):412-5. PMID: 8872515
p56lck, a member of the src family of non-receptor protein receptor kinases, is required for normal signal transduction through the T cell receptor. Inappropriate T cell activation and proliferation has...
6.
Wilkinson S, Morath M, Bennett D, Burgess M, Isaacs D
J Paediatr Child Health . 1996 Feb; 32(1):60-2. PMID: 8652217
Objective: To perform a feasibility and immunogenicity study of an accelerated schedule of hepatitis B immunization for high-risk youth. Methodology: High-risk adolescents attending a youth health centre and nearby youth...
7.
Wilkinson S, Hallam T
Methods Mol Biol . 1995 Jan; 41:261-70. PMID: 7655562
No abstract available.
8.
Brotherick I, Lennard T, Wilkinson S, Cook S, Angus B, Shenton B
Cytometry . 1994 Jul; 16(3):262-9. PMID: 7924696
A method for the purification, conjugation, and use of EGF-R antibody to quantify EGF receptors on tumour cells by flow cytometry is described. The quantification of both internal and external...
9.
Wilkinson S, Hallam T
Trends Pharmacol Sci . 1994 Feb; 15(2):53-7. PMID: 8165725
Evidence has emerged over the past decade to suggest that protein kinase C (PKC) is a widespread family of kinases responsible for many diverse and critical cellular functions. With the...
10.
Wilkinson S, Parker P, Nixon J
Biochem J . 1993 Sep; 294 ( Pt 2):335-7. PMID: 8373348
The protein kinase C (PKC) family of isoenzymes is believed to mediate a wide range of signal-transduction pathways in many different cell types. A series of bisindolylmaleimides have been evaluated...