S Boast
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Explore the profile of S Boast including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
747
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Recent Articles
1.
Li B, Boast S, de los Santos K, Schieren I, Quiroz M, Teitelbaum S, et al.
Nat Genet
. 2000 Mar;
24(3):304-8.
PMID: 10700189
The c-Abl protein is a non-receptor tyrosine kinase involved in many aspects of mammalian development. c-Abl kinase is widely expressed, but high levels are found in hyaline cartilage in the...
2.
Lu Q, Gore M, Zhang Q, Camenisch T, Boast S, Casagranda F, et al.
Nature
. 1999 May;
398(6729):723-8.
PMID: 10227296
We have generated and analysed null mutations in the mouse genes encoding three structurally related receptors with tyrosine kinase activity: Tyro 3, Axl, and Mer. Mice lacking any single receptor,...
3.
Zhang Q, Boast S, de los Santos K, Begemann M, Goff S
J Virol
. 1996 Nov;
70(11):8089-97.
PMID: 8892934
Retroviral genomes encoding a portion of the Moloney murine leukemia virus Gag protein fused to portions of the murine axl cDNA were constructed so as to mimic naturally occurring transforming...
4.
Hardin J, Boast S, Schwartzberg P, Lee G, Alt F, Stall A, et al.
Cell Immunol
. 1996 Aug;
172(1):100-7.
PMID: 8806812
The proto-oncogene c-abl encodes a tyrosine kinase that is hypothesized to function in proliferation-stimulatory signaling pathways. Previous work on mice homozygous for targeted mutations in the c-abl gene (ablml and...
5.
Transgenes encoding both type I and type IV c-abl proteins rescue the lethality of c-abl mutant mice
Hardin J, Boast S, Mendelsohn M, de los Santos K, Goff S
Oncogene
. 1996 Jun;
12(12):2669-77.
PMID: 8700526
Mice carrying homozygous mutations in the c-abl gene (abl-(m1) or abl2) exhibit severe, though variable phenotypes, including a high rate of postnatal mortality, runting, morphological abnormalities, a susceptibility to infections,...
6.
Hardin J, Boast S, Schwartzberg P, Lee G, Alt F, Stall A, et al.
Cell Immunol
. 1995 Oct;
165(1):44-54.
PMID: 7671324
Mice homozygous for a mutation in the c-abl tyrosine kinase gene have multiple defects including high postnatal mortality, runting, morphological abnormalities, susceptibility to infections, and reductions in lymphocytes and their...
7.
Mackarehtschian K, Hardin J, Moore K, Boast S, Goff S, Lemischka I
Immunity
. 1995 Jul;
3(1):147-61.
PMID: 7621074
The flk2 receptor tyrosine kinase has been implicated in hematopoietic development. Mice deficient in flk2 were generated. Mutants developed into healthy adults with normal mature hematopoietic populations. However, they possessed...
8.
Wong K, Hardin J, Boast S, Cooper C, Merrell K, Doyle T, et al.
Oncogene
. 1995 Feb;
10(4):705-11.
PMID: 7862448
c-Abl, a nonreceptor tyrosine kinase, appears to play a role in cell cycle progression, cell proliferation and differentiation. Mice homozygous for a mutation in c-abl (ablml), show pleiotropic abnormalities, including...
9.
Parker M, Smith A, Mundell K, Collins M, Boast S, Ramirez F
Nucleic Acids Res
. 1992 Nov;
20(21):5825-30.
PMID: 1333588
The goal of this study was to determine whether alpha 2(1) procollagen gene expression is modulated by positive or negative trans-acting DNA-binding proteins. Previous studies have shown that a clone...
10.
Schwartzberg P, Stall A, Hardin J, Bowdish K, Humaran T, Boast S, et al.
Cell
. 1991 Jun;
65(7):1165-75.
PMID: 2065353
The c-abl gene, originally identified as the cellular homolog of the transforming gene of the Abelson murine leukemia virus, encodes a protein-tyrosine kinase of unknown function that is expressed in...