J D Hardin
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Explore the profile of J D Hardin including associated specialties, affiliations and a list of published articles.
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9
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541
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Recent Articles
1.
Koppen M, Simske J, Sims P, Firestein B, Hall D, Radice A, et al.
Nat Cell Biol
. 2001 Nov;
3(11):983-91.
PMID: 11715019
The function of epithelial cell sheets depends on the integrity of specialized cell-cell junctions that connect neighbouring cells. We have characterized the novel coiled-coil protein AJM-1, which localizes to an...
2.
MOHLER W, Simske J, Hardin J, White J
Curr Biol
. 1998 Oct;
8(19):1087-90.
PMID: 9768364
Cell fusions produce multinucleate syncytia that are crucial to the structure of essential tissues in many organisms [1-5]. In humans the entire musculature, much of the placenta, and key cells...
3.
Hardin J, Boast S, Schwartzberg P, Lee G, Alt F, Stall A, et al.
Cell Immunol
. 1996 Aug;
172(1):100-7.
PMID: 8806812
The proto-oncogene c-abl encodes a tyrosine kinase that is hypothesized to function in proliferation-stimulatory signaling pathways. Previous work on mice homozygous for targeted mutations in the c-abl gene (ablml and...
4.
Transgenes encoding both type I and type IV c-abl proteins rescue the lethality of c-abl mutant mice
Hardin J, Boast S, Mendelsohn M, de los Santos K, Goff S
Oncogene
. 1996 Jun;
12(12):2669-77.
PMID: 8700526
Mice carrying homozygous mutations in the c-abl gene (abl-(m1) or abl2) exhibit severe, though variable phenotypes, including a high rate of postnatal mortality, runting, morphological abnormalities, a susceptibility to infections,...
5.
Hardin J, Boast S, Schwartzberg P, Lee G, Alt F, Stall A, et al.
Cell Immunol
. 1995 Oct;
165(1):44-54.
PMID: 7671324
Mice homozygous for a mutation in the c-abl tyrosine kinase gene have multiple defects including high postnatal mortality, runting, morphological abnormalities, susceptibility to infections, and reductions in lymphocytes and their...
6.
Mackarehtschian K, Hardin J, Moore K, Boast S, Goff S, Lemischka I
Immunity
. 1995 Jul;
3(1):147-61.
PMID: 7621074
The flk2 receptor tyrosine kinase has been implicated in hematopoietic development. Mice deficient in flk2 were generated. Mutants developed into healthy adults with normal mature hematopoietic populations. However, they possessed...
7.
Wong K, Hardin J, Boast S, Cooper C, Merrell K, Doyle T, et al.
Oncogene
. 1995 Feb;
10(4):705-11.
PMID: 7862448
c-Abl, a nonreceptor tyrosine kinase, appears to play a role in cell cycle progression, cell proliferation and differentiation. Mice homozygous for a mutation in c-abl (ablml), show pleiotropic abnormalities, including...
8.
Schwartzberg P, Stall A, Hardin J, Bowdish K, Humaran T, Boast S, et al.
Cell
. 1991 Jun;
65(7):1165-75.
PMID: 2065353
The c-abl gene, originally identified as the cellular homolog of the transforming gene of the Abelson murine leukemia virus, encodes a protein-tyrosine kinase of unknown function that is expressed in...
9.
Hardin J
Dev Biol
. 1987 May;
121(1):253-62.
PMID: 3552789
Earlier studies using colchicine (L. G. Tilney and J. R. Gibbins, 1969, J. Cell Sci. 5, 195-210) had suggested that intact microtubules (MTs) are necessary for archenteron elongation during the...