P L Schwartzberg
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Explore the profile of P L Schwartzberg including associated specialties, affiliations and a list of published articles.
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33
Citations
1983
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Recent Articles
1.
Marom A, Barak A, Kramer M, Lewinsky H, Binsky-Ehrenreich I, Cohen S, et al.
Oncogene
. 2016 Jul;
36(5):628-638.
PMID: 27452524
Chronic lymphocytic leukemia (CLL) is a malignant disease of small mature lymphocytes. Signals from the CLL microenvironment promote progression of the disease and induce drug resistance. This phenomenon is largely...
2.
Sood R, Bader P, Speer M, Edwards Y, Eddings E, Blair R, et al.
Cytogenet Genome Res
. 2004 Jun;
106(1):61-7.
PMID: 15218243
Here we report on a male patient with sacral dysgenesis (SD) and constitutional pericentric inversion of chromosome 6 (p11.2;q23.3). SD is a heterogeneous group of congenital anomalies with complex genetic...
3.
Czar M, Debnath J, Schaeffer E, Lewis C, Schwartzberg P
Biochem Soc Trans
. 2001 Nov;
29(Pt 6):863-7.
PMID: 11709089
The Tec kinases have been implicated as important components of signalling pathways downstream of lymphocyte antigen receptors. Activation of these kinases requires two steps: (i) phosphorylation by Src family kinases...
4.
Schaeffer E, Yap G, Lewis C, Czar M, McVicar D, CHEEVER A, et al.
Nat Immunol
. 2001 Nov;
2(12):1183-8.
PMID: 11702066
The Tec kinases Rlk and Itk are critical for full T cell receptor (TCR)-induced activation of phospholipase C-gamma and mitogen-activated protein kinase. We show here that the mutation of Rlk...
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Lewis C, Broussard C, Czar M, Schwartzberg P
Curr Opin Immunol
. 2001 Jun;
13(3):317-25.
PMID: 11406363
The Tec kinases are implicated as important components of the antigen receptor signaling required for proper lymphocyte activation and development. Recent data suggest that these kinases contribute to multiprotein complexes...
8.
Czar M, Kersh E, Mijares L, Lanier G, Lewis J, Yap G, et al.
Proc Natl Acad Sci U S A
. 2001 Jun;
98(13):7449-54.
PMID: 11404475
We have introduced a targeted mutation in SH2D1A/DSHP/SAP, the gene responsible for the human genetic disorder X-linked lymphoproliferative disease (XLP). SLAM-associated protein (SAP)-deficient mice had normal lymphocyte development, but on...
9.
Chamorro M, Czar M, Debnath J, Cheng G, Lenardo M, Varmus H, et al.
BMC Immunol
. 2001 May;
2:3.
PMID: 11353545
Background: The Tec family kinases are implicated in signaling from lymphocyte antigen receptors and are activated following phosphorylation by Src kinases. For most Tec kinases, this activation requires an interaction...
10.
Xing L, Venegas A, Chen A, Boyce B, Varmus H, Schwartzberg P
Genes Dev
. 2001 Feb;
15(2):241-53.
PMID: 11157779
Mutant src(-/-) mice have osteopetrosis resulting from defective osteoclasts, the cells that resorb bone. However, signaling pathways involving Src family members in osteoclasts remain unclear. We demonstrate that expression of...