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S A Hughes

Explore the profile of S A Hughes including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 1048
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Recent Articles
1.
Redman A, Parkerton T, Butler J, Letinski D, Frank R, Hewitt L, et al.
Environ Sci Technol . 2018 Jun; 52(14):8039-8049. PMID: 29902380
Oil sand operations in Alberta, Canada will eventually include returning treated process-affected waters to the environment. Organic constituents in oil sand process-affected water (OSPW) represent complex mixtures of nonionic and...
2.
Hughes S, Shewry P, Li L, Gibson G, Sanz M, Rastall R
J Agric Food Chem . 2007 May; 55(11):4589-95. PMID: 17488118
The fermentation of three arabinoxylan (AX) fractions from wheat by the human fecal microflora was investigated in vitro. Three AX fractions, with average molecular masses of 354, 278, and 66...
3.
Larkin J, Hughes S, Beirne D, Patel P, Gibbens I, Bate S, et al.
Br J Cancer . 2006 Dec; 96(1):44-8. PMID: 17146474
Temozolomide is an alkylating agent with activity in the treatment of melanoma metastatic to the brain. Lomustine is a nitrosurea that crosses the blood brain barrier and there is evidence...
4.
Richards D, Hughes S, Irving M, Scott N
Colorectal Dis . 2003 Jun; 3(4):223-6. PMID: 12790963
Objective: To measure quality of life (QoL), using validated health status instruments, of patients with functioning IPAA for CUC. Patients And Methods: Between 1986 and 1997, a total of 77...
5.
Carothers A, Hughes S, Ortega D, Bertagnolli M
Cancer Lett . 2002 Oct; 187(1-2):77-86. PMID: 12359354
Menopausal estrogen replacement therapy is thought to be responsible for the recent decline in colorectal cancer (CRC) incidence among women. In the C57BL/6J-Min/+ mouse, an animal model of CRC, 17beta-estradiol...
6.
Hughes S, GIBSON W, Young J
Naunyn Schmiedebergs Arch Pharmacol . 2001 Jan; 362(6):555-8. PMID: 11138848
U-73122, an N-aminosteroid homologue of N-ethylmaleimide (NEM), widely used as an inhibitor of phospholipase C, was found to be a potent inhibitor (IC50 5.5+/-0.5 microM) of the binding of [3H]mepyramine...
7.
Hughes S
Phys Rev Lett . 2001 Jan; 85(25):5480. PMID: 11136026
No abstract available.
8.
Calver A, Medhurst A, Robbins M, Charles K, Evans M, Harrison D, et al.
Neuroscience . 2000 Sep; 100(1):155-70. PMID: 10996466
GABA(B) receptors are G-protein-coupled receptors that mediate the slow and prolonged synaptic actions of GABA in the CNS via the modulation of ion channels. Unusually, GABA(B) receptors form functional heterodimers...
9.
Davis J, Gray J, Gunthorpe M, Hatcher J, Davey P, Overend P, et al.
Nature . 2000 May; 405(6783):183-7. PMID: 10821274
The vanilloid receptor-1 (VR1) is a ligand-gated, non-selective cation channel expressed predominantly by sensory neurons. VR1 responds to noxious stimuli including capsaicin, the pungent component of chilli peppers, heat and...
10.
Bonilla P, Hughes S, Weiss S
J Virol . 1997 Feb; 71(2):900-9. PMID: 8995606
The 21.7-kb replicase locus of mouse hepatitis virus strain A59 (MHV-A59) encodes several putative functional domains, including three proteinase domains. Encoded closest to the 5' terminus of this locus is...