Ryotaro Saiki
Overview
Explore the profile of Ryotaro Saiki including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
268
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0
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Recent Articles
1.
Kumamoto T, Nakajima M, Uga R, Ihayazaka N, Kashihara H, Katakawa K, et al.
Bioorg Med Chem
. 2017 Dec;
26(3):603-608.
PMID: 29277306
N-Methyl-d-aspartate (NMDA) receptors have been implicated in learning and memory, and may also play a central role in various conditions leading to neuronal degradation. NMDA receptor antagonists could therefore be...
2.
Yoshida M, Kato N, Uemura T, Mizoi M, Nakamura M, Saiki R, et al.
eNeurologicalSci
. 2017 Dec;
7:18-24.
PMID: 29260020
Objective: Measurement of plasma levels of protein-conjugated acrolein (PC-Acro) together with IL-6 and CRP can be used to identify silent brain infarction (SBI) with high sensitivity and specificity. The aim...
3.
Uemura T, Suzuki T, Saiki R, Dohmae N, Ito S, Takahashi H, et al.
Int J Biochem Cell Biol
. 2017 May;
88:84-91.
PMID: 28483671
We have recently reported that the altered recognition patterns of immunoglobulins due to acrolein conjugation are at least partially responsible for autoimmune diseases in patients with primary Sjögren's syndrome (pSS)....
4.
Uemura T, Watanabe K, Ishibashi M, Saiki R, Kuni K, Nishimura K, et al.
Biochem Biophys Res Commun
. 2016 Apr;
473(2):630-5.
PMID: 27037020
We previously reported that tissue damage during brain infarction was mainly caused by inactivation of proteins by acrolein. This time, it was tested why brain infarction increases in parallel with...
5.
Nakamura M, Uemura T, Saiki R, Sakamoto A, Park H, Nishimura K, et al.
Atherosclerosis
. 2015 Dec;
244:131-7.
PMID: 26630182
Background And Purpose: N-Methyl-d-aspartate (NMDA) receptors have a high permeability to Ca(2+), contributing to neuronal cell death after stroke. We recently found that acrolein produced from polyamines is a major...
6.
Hirose T, Saiki R, Uemura T, Suzuki T, Dohmae N, Ito S, et al.
Clin Chim Acta
. 2015 Aug;
450:184-9.
PMID: 26301996
Background: We previously reported that the level of protein-conjugated acrolein (PC-Acro), a marker of cell or tissue damage, was increased in saliva from patients with primary Sjögren's syndrome (pSS), and...
7.
Hirose T, Saiki R, Yoshizawa Y, Imamura M, Higashi K, Ishii I, et al.
Biochem Biophys Res Commun
. 2015 Jun;
463(4):1190-5.
PMID: 26086092
N-Methyl-D-aspartate receptors (NMDA receptors) are known to be permeable to Na(+) and Ca(2+) ions. In this study, we tested whether polyamines (putrescine, spermidine, spermine), organic cations found in cells, can...
8.
Suabjakyong P, Saiki R, Van Griensven L, Higashi K, Nishimura K, Igarashi K, et al.
PLoS One
. 2015 Mar;
10(3):e0122733.
PMID: 25811373
The basidiomycetous mushroom Phellinus igniarius (L.) Quel. has been used as traditional medicine in various Asian countries for many years. Although many reports exist on its anti-oxidative and anti-inflammatory activities...
9.
Yoshida M, Higashi K, Kuni K, Mizoi M, Saiki R, Nakamura M, et al.
Clin Chim Acta
. 2014 Dec;
441:115-21.
PMID: 25542982
Background: We previously reported that the level of urinary 3-hydroxypropyl mercapturic acid (3-HPMA)/creatinine (Cre) was reduced following stroke. The aim of this study was to determine whether the level of...
10.
Higashi K, Imamura M, Fudo S, Uemura T, Saiki R, Hoshino T, et al.
PLoS One
. 2014 Jul;
9(7):e102234.
PMID: 25019617
Polyamine (putrescine, spermidine and spermine) and agmatine uptake by the human organic cation transporter 2 (hOCT2) was studied using HEK293 cells transfected with pCMV6-XL4/hOCT2. The Km values for putrescine and...