» Authors » Ryan Wallis

Ryan Wallis

Explore the profile of Ryan Wallis including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 10
Citations 93
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Hughes B, Davis A, Milligan D, Wallis R, Mossa F, Philpott M, et al.
Genome Med . 2025 Jan; 17(1):2. PMID: 39810225
Background: Senescence classification is an acknowledged challenge within the field, as markers are cell-type and context dependent. Currently, multiple morphological and immunofluorescence markers are required. However, emerging scRNA-seq datasets have...
2.
OSullivan E, Wallis R, Mossa F, Bishop C
NPJ Aging . 2024 Sep; 10(1):41. PMID: 39277623
Senescence is an anti-tumour mechanism and hallmark of cancer. Loss or mutation of key senescence effectors, such as p16INK4A, are frequently observed in cancer. Intriguingly, some human tumours are both...
3.
Duran I, Bishop C, Gil J, Wallis R
Nat Aging . 2024 Aug; 4(9):1167-1170. PMID: 39187617
No abstract available.
4.
Wallis R, Bishop C
Cell Metab . 2023 Oct; 35(10):1675-1676. PMID: 37793342
Killing senescent cells to improve health-span holds great promise. However, screening for senescence-regulating genes and molecules is challenging because these cells do not proliferate. In this issue, Colville and Liu...
5.
Hughes B, Wallis R, Bishop C
Cell Tissue Res . 2023 Apr; 394(1):1-16. PMID: 37016180
Senescence is a widely appreciated tumour suppressive mechanism, which acts as a barrier to cancer development by arresting cell cycle progression in response to harmful stimuli. However, senescent cell accumulation...
6.
Wallis R, Milligan D, Hughes B, Mizen H, Lopez-Dominguez J, Eduputa U, et al.
Aging (Albany NY) . 2022 May; 14(10):4220-4246. PMID: 35580013
Senescence occurs in response to a number of damaging stimuli to limit oncogenic transformation and cancer development. As no single, universal senescence marker has been discovered, the confident classification of...
7.
Rutting S, Badal T, Wallis R, Schoeffel R, Roche N, Cottee A, et al.
Eur Respir J . 2021 Mar; 58(1). PMID: 33766946
No abstract available.
8.
Wallis R, Josipovic N, Mizen H, Robles-Tenorio A, Tyler E, Papantonis A, et al.
J Extracell Vesicles . 2021 Mar; 10(4):e12041. PMID: 33659050
A hallmark of senescence is the acquisition of an enhanced secretome comprising inflammatory mediators and tissue remodelling agents - the senescence-associated secretory phenotype (SASP). Through the SASP, senescent cells are...
9.
Tyler E, Gutierrez Del Arroyo A, Hughes B, Wallis R, Garbe J, Stampfer M, et al.
Aging Cell . 2021 Feb; 20(3):e13318. PMID: 33547862
Senescence, a state of stable growth arrest, plays an important role in ageing and age-related diseases in vivo. Although the INK4/ARF locus is known to be essential for senescence programmes,...
10.
Wallis R, Mizen H, Bishop C
Mech Ageing Dev . 2020 May; 189:111263. PMID: 32461143
Senescence is a state of proliferative arrest which has been described as a protective mechanism against the malignant transformation of cells. However, senescent cells have also been demonstrated to accumulate...