Ryan Powles
Overview
Explore the profile of Ryan Powles including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
113
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0
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Recent Articles
1.
DGKα/ζ inhibitors combine with PD-1 checkpoint therapy to promote T cell-mediated antitumor immunity
Wichroski M, Benci J, Liu S, Chupak L, Fang J, Cao C, et al.
Sci Transl Med
. 2023 Oct;
15(719):eadh1892.
PMID: 37878674
Programmed cell death protein 1 (PD-1) immune checkpoint blockade therapy has revolutionized cancer treatment. Although PD-1 blockade is effective in a subset of patients with cancer, many fail to respond...
2.
Hu Y, Lu Q, Powles R, Yao X, Yang C, Fang F, et al.
PLoS Comput Biol
. 2017 Jun;
13(6):e1005589.
PMID: 28594818
Genetic risk prediction is an important goal in human genetics research and precision medicine. Accurate prediction models will have great impacts on both disease prevention and early treatment strategies. Despite...
3.
Souilmi Y, Lancaster A, Jung J, Rizzo E, Hawkins J, Powles R, et al.
BMC Med Genomics
. 2015 Oct;
8:64.
PMID: 26470712
Background: While next-generation sequencing (NGS) costs have plummeted in recent years, cost and complexity of computation remain substantial barriers to the use of NGS in routine clinical care. The clinical...