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Ryan G Thys

Explore the profile of Ryan G Thys including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 139
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Recent Articles
1.
Szlachta K, Thys R, Atkin N, Pierce L, Bekiranov S, Wang Y
Genome Biol . 2018 Jul; 19(1):89. PMID: 30001206
Background: Alternative DNA secondary structures can arise from single-stranded DNA when duplex DNA is unwound during DNA processes such as transcription, resulting in the regulation or perturbation of these processes....
2.
Thys R, Lehman C, Pierce L, Wang Y
Mutat Res . 2015 Jul; 779:86-95. PMID: 26163765
Hematopoietic stem and progenitor cells (HSPCs) give rise to all of the cells that make up the hematopoietic system in the human body, making their stability and resilience especially important....
3.
Thys R, Lehman C, Pierce L, Wang Y
Curr Genomics . 2015 May; 16(1):60-70. PMID: 25937814
DNA has the ability to form a variety of secondary structures that can interfere with normal cellular processes, and many of these structures have been associated with neurological diseases and...
4.
Giri B, Smaldino P, Thys R, Creacy S, Routh E, Hantgan R, et al.
Nucleic Acids Res . 2011 May; 39(16):7161-78. PMID: 21586581
It has been previously shown that the DHX36 gene product, G4R1/RHAU, tightly binds tetramolecular G4-DNA with high affinity and resolves these structures into single strands. Here, we test the ability...