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Yoshikuni Nagamine

Explore the profile of Yoshikuni Nagamine including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 1146
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Recent Articles
1.
Chen X, Yuan J, Xue G, Campanario S, Wang D, Wang W, et al.
Nat Commun . 2021 Aug; 12(1):5043. PMID: 34413292
Skeletal muscle has a remarkable ability to regenerate owing to its resident stem cells (also called satellite cells, SCs). SCs are normally quiescent; when stimulated by damage, they activate and...
2.
Nie J, Jiang M, Zhang X, Tang H, Jin H, Huang X, et al.
Cell Rep . 2015 Oct; 13(4):723-732. PMID: 26489465
RNA G-quadruplexes (G4s) play important roles in RNA biology. However, the function and regulation of mRNA G-quadruplexes in embryonic development remain elusive. Previously, we identified RHAU (DHX36, G4R1) as an...
3.
Yoo J, Takahasi K, Ng C, Ouda R, Onomoto K, Yoneyama M, et al.
PLoS Pathog . 2014 Mar; 10(3):e1004012. PMID: 24651521
RIG-I is a DExD/H-box RNA helicase and functions as a critical cytoplasmic sensor for RNA viruses to initiate antiviral interferon (IFN) responses. Here we demonstrate that another DExD/H-box RNA helicase...
4.
Lai J, Ponti S, Pan D, Kohler H, Skoda R, Matthias P, et al.
Blood . 2012 Mar; 119(18):4291-300. PMID: 22422825
The DEAH helicase RHAU (alias DHX36, G4R1) is the only helicase shown to have G-quadruplex (G4)-RNA resolvase activity and the major source of G4-DNA resolvase activity. Previous report showed RHAU...
5.
Huang W, Smaldino P, Zhang Q, Miller L, Cao P, Stadelman K, et al.
Nucleic Acids Res . 2011 Oct; 40(3):1033-49. PMID: 21993297
Yin Yang 1 (YY1) is a multifunctional protein with regulatory potential in tumorigenesis. Ample studies demonstrated the activities of YY1 in regulating gene expression and mediating differential protein modifications. However,...
6.
Lattmann S, Stadler M, Vaughn J, Akman S, Nagamine Y
Nucleic Acids Res . 2011 Aug; 39(21):9390-404. PMID: 21846770
Guanine-quadruplexes (G4) consist of non-canonical four-stranded helical arrangements of guanine-rich nucleic acid sequences. The bulky and thermodynamically stable features of G4 structures have been shown in many respects to affect...
7.
Giri B, Smaldino P, Thys R, Creacy S, Routh E, Hantgan R, et al.
Nucleic Acids Res . 2011 May; 39(16):7161-78. PMID: 21586581
It has been previously shown that the DHX36 gene product, G4R1/RHAU, tightly binds tetramolecular G4-DNA with high affinity and resolves these structures into single strands. Here, we test the ability...
8.
Clark J, Faisal A, Baliga R, Nagamine Y, Arany I
Cancer Lett . 2010 Jun; 297(2):165-70. PMID: 20547441
The extracellular signal-regulated kinase (ERK) has been shown to mediate cisplatin (CP)-induced toxicity to renal proximal tubule cells. Here, we demonstrate that ERK serves as the kinase that phosphorylates the...
9.
Lattmann S, Giri B, Vaughn J, Akman S, Nagamine Y
Nucleic Acids Res . 2010 May; 38(18):6219-33. PMID: 20472641
Under physiological conditions, guanine-rich sequences of DNA and RNA can adopt stable and atypical four-stranded helical structures called G-quadruplexes (G4). Such G4 structures have been shown to occur in vivo...
10.
Stasinopoulos S, Mariasegaram M, Gafforini C, Nagamine Y, Medcalf R
FEBS J . 2010 Apr; 277(5):1331-44. PMID: 20392207
Plasminogen activator inhibitor type 2 (PAI-2; SERPINB2) is a highly-regulated gene that is subject to both transcriptional and post-transcriptional control. For the latter case, inherent PAI-2 mRNA instability was previously...