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Ruani N Fernando

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Articles 13
Citations 377
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Recent Articles
1.
van Hameren G, Gonzalez S, Fernando R, Perrin-Tricaud C, Tricaud N
Methods Mol Biol . 2018 Jul; 1791:263-276. PMID: 30006717
Myelinated fibers are essential for the rapid and efficient propagation of nerve information throughout the body. These fibers result from an intimate crosstalk between myelinating glia and the myelinated axons...
2.
Fernando R, Cotter L, Perrin-Tricaud C, Berthelot J, Bartolami S, Pereira J, et al.
Nat Commun . 2016 Jul; 7:12186. PMID: 27435623
Fast nerve conduction relies on successive myelin segments that electrically isolate axons. Segment geometry-diameter and length-is critical for the optimization of nerve conduction and the molecular mechanisms allowing this optimized...
3.
Fernando R, Chaudhari U, Escher S, Hengstler J, Hescheler J, Jennings P, et al.
Arch Toxicol . 2016 May; 90(6):1529-1539. PMID: 27129694
SEURAT-1 is a joint research initiative between the European Commission and Cosmetics Europe aiming to develop in vitro- and in silico-based methods to replace the in vivo repeated dose systemic...
4.
Gonzalez S, Fernando R, Perrin-Tricaud C, Tricaud N
Nat Protoc . 2014 Apr; 9(5):1160-9. PMID: 24762783
The myelin sheath is essential for the rapid and efficient propagation of action potentials. However, our understanding of the basic molecular mechanisms that regulate myelination, demyelination and remyelination is limited....
5.
Albiston A, Diwakarla S, Fernando R, Mountford S, Yeatman H, Morgan B, et al.
Br J Pharmacol . 2011 Apr; 164(1):37-47. PMID: 21470200
Two structurally distinct peptides, angiotensin IV and LVV-haemorphin 7, both competitive high-affinity inhibitors of insulin-regulated aminopeptidase (IRAP), were found to enhance aversion-associated and spatial memory in normal rats and to...
6.
Fernando R, Eleuteri B, Abdelhady S, Nussenzweig A, Andang M, Ernfors P
Proc Natl Acad Sci U S A . 2011 Mar; 108(14):5837-42. PMID: 21436033
Adult neural stem cell proliferation is dynamic and has the potential for massive self-renewal yet undergoes limited cell division in vivo. Here, we report an epigenetic mechanism regulating proliferation and...
7.
Albiston A, Yeatman H, Pham V, Fuller S, Diwakarla S, Fernando R, et al.
Regul Pept . 2010 Sep; 166(1-3):83-9. PMID: 20851149
The physiological importance of the insulin responsive glucose transporter GLUT4 in adipocytes and muscle in maintaining glucose homeostasis is well established. A key protein associated with this process is the...
8.
Albiston A, Fernando R, Yeatman H, Burns P, Ng L, Daswani D, et al.
Neurobiol Learn Mem . 2009 Aug; 93(1):19-30. PMID: 19660563
The AT(4) ligands, angiotensin IV and LVV-hemorphin 7, elicit robust effects on facilitating memory by binding to a specific site in the brain historically termed the angiotensin AT(4) receptor. The...
9.
Albiston A, Morton C, Ng H, Pham V, Yeatman H, Ye S, et al.
FASEB J . 2008 Aug; 22(12):4209-17. PMID: 18716029
Approximately one-quarter of people over the age of 65 are estimated to suffer some form of cognitive impairment, underscoring the need for effective cognitive-enhancing agents. Insulin-regulated aminopeptidase (IRAP) is potentially...
10.
Fernando R, Albiston A, Chai S
Eur J Neurosci . 2008 Aug; 28(3):588-98. PMID: 18702730
It is proposed that insulin-regulated aminopeptidase (IRAP) is the site of action of two peptides, angiotensin IV and LVV-hemorphin 7, which have facilitatory effects on learning and memory. In fat...