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Anthony L Albiston

Explore the profile of Anthony L Albiston including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 704
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Recent Articles
1.
Burns P, Bowditch J, McFadyen J, Loiacono R, Albiston A, Pham V, et al.
Behav Brain Res . 2019 Aug; 376:112150. PMID: 31419522
Oxytocin, and the closely related neuropeptide, vasopressin, are both known to modulate social behaviours. The pro-social effects of oxytocin are well-documented and have generated much interest into its suitability as...
2.
Albiston A, Cacador M, Sinnayah P, Burns P, Chai S
J Mol Endocrinol . 2017 Mar; 58(4):193-198. PMID: 28356324
Insulin-regulated aminopeptidase (IRAP) co-localizes with the glucose transporter 4 (GLUT4) in GLUT4 storage vesicles (GSV) in insulin-responsive cells. In response to insulin, IRAP is the only transmembrane enzyme known to...
3.
Yeatman H, Albiston A, Burns P, Chai S
Neurobiol Learn Mem . 2016 Nov; 136:174-182. PMID: 27713012
Central infusion of Insulin-Regulated Aminopeptidase (IRAP) inhibitors improves memory in both normal rodents and in models of memory deficit. However, in contrast, the global IRAP knockout mice (KO) demonstrate age-accelerated...
4.
Seyer B, Pham V, Albiston A, Chai S
Neurosci Lett . 2016 Jun; 628:171-8. PMID: 27345383
Indwelling cannulas are often used to deliver pharmacological agents into the lateral ventricles of the brain to study their effects on memory and learning, yet little is known about the...
5.
Mountford S, Albiston A, Charman W, Ng L, Holien J, Parker M, et al.
J Med Chem . 2014 Jan; 57(4):1368-77. PMID: 24471437
Peptide inhibitors of insulin-regulated aminopeptidase (IRAP) enhance fear avoidance and spatial memory and accelerate spatial learning in a number of memory paradigms. Using a virtual screening approach, a series of...
6.
Morgan B, Chai S, Albiston A
Recent Pat Endocr Metab Immune Drug Discov . 2011 Nov; 5(1):25-32. PMID: 22074575
Type 2 diabetes is a complex, multifactorial disease resulting from insulin resistance in target tissues and the impairment of insulin secretion from the pancreas. One of the key metabolic actions...
7.
Pham V, Albiston A, Downes C, Wong C, Diwakarla S, Ng L, et al.
J Neurotrauma . 2011 Sep; 29(6):1243-8. PMID: 21895534
Recent studies have demonstrated that angiotensin IV (Ang IV) provides protection against brain injury caused by cerebral ischemia. Ang IV is a potent inhibitor of insulin-regulated aminopeptidase (IRAP). Therefore, we...
8.
Albiston A, Diwakarla S, Fernando R, Mountford S, Yeatman H, Morgan B, et al.
Br J Pharmacol . 2011 Apr; 164(1):37-47. PMID: 21470200
Two structurally distinct peptides, angiotensin IV and LVV-haemorphin 7, both competitive high-affinity inhibitors of insulin-regulated aminopeptidase (IRAP), were found to enhance aversion-associated and spatial memory in normal rats and to...
9.
Yang R, Smolders I, Vanderheyden P, Demaegdt H, Van Eeckhaut A, Vauquelin G, et al.
Hypertension . 2011 Apr; 57(5):956-64. PMID: 21464395
Recently, a new derivative of angiotensin (Ang) II, called "Ang A," has been discovered to be present in plasma of healthy humans and, in increased concentrations, in end-stage renal failure...
10.
Ascher D, Cromer B, Morton C, Volitakis I, Cherny R, Albiston A, et al.
Biochemistry . 2011 Feb; 50(13):2611-22. PMID: 21348480
The development of inhibitors of insulin-regulated aminopeptidase (IRAP), a membrane-bound zinc metallopeptidase, is a promising approach for the discovery of drugs for the treatment of memory loss such as that...