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Rosario Casale

Explore the profile of Rosario Casale including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 293
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Recent Articles
1.
Cautela D, De Sio F, Balestrieri M, Casale R, Laratta B, Castaldo D, et al.
J Sci Food Agric . 2020 Aug; 101(3):981-988. PMID: 32761816
Background: The so-called 'Neapolitan limmo' or 'lemoncetta Locrese' is an old and now rare Mediterranean sweet lime, similar to lemon but smaller. It is a fruit distinguished from orange, lemon,...
2.
DOnofrio N, Balestrieri A, Neglia G, Monaco A, Tatullo M, Casale R, et al.
J Agric Food Chem . 2019 Jan; 67(6):1702-1710. PMID: 30661355
δ-Valerobetaine (δVB), a constitutive metabolite of ruminant milk, is produced in the rumen from free dietary N- trimethyllysine occurring ubiquitously in vegetable kingdom. The biological role of δVB is poorly...
3.
Servillo L, DOnofrio N, Neglia G, Casale R, Cautela D, Marrelli M, et al.
J Agric Food Chem . 2018 Jul; 66(30):8142-8149. PMID: 30011990
Ruminants' milk contains δ-valerobetaine originating from rumen through the transformation of dietary N-trimethyllysine. Among ruminant's milk, the occurrence of δ-valerobetaine, along with carnitine precursors and metabolites, has not been investigated...
4.
Servillo L, DOnofrio N, Giovane A, Casale R, Cautela D, Castaldo D, et al.
Food Chem . 2018 Apr; 260:193-199. PMID: 29699662
Quaternary ammonium compounds containing N-trimethylamino moiety, such as choline derivatives and carnitine, abundant in meat and dairy products, are metabolic precursors of trimethylamine (TMA). A similar fate is reported for...
5.
Servillo L, Castaldo D, Giovane A, Casale R, DOnofrio N, Cautela D, et al.
Biochim Biophys Acta Gen Subj . 2018 Feb; 1862(4):991-998. PMID: 29413907
Background: Ophthalmic acid (OPH), γ-glutamyl-L-2-aminobutyryl-glycine, a tripeptide analogue of glutathione (GSH), has recently captured considerable attention as a biomarker of oxidative stress in animals. The OPH and GSH biosynthesis, as...
6.
Severino B, Corvino A, Fiorino F, Luciano P, Frecentese F, Magli E, et al.
Eur J Med Chem . 2017 Nov; 143:1677-1686. PMID: 29133036
Hydrogen sulfide (HS) is an endogenous modulator that plays significant physio-pathological roles in several biological systems. In this research field there is a large interest in developing selective CBS and...
7.
Servillo L, DOnofrio N, Giovane A, Casale R, Cautela D, Ferrari G, et al.
Food Chem . 2017 Sep; 239:234-241. PMID: 28873565
We report the LC-ESI-MS/MS determination of betaines in commercial flours of cereals and pseudocereals most utilized in human nutrition. Results showed that glycine betaine, trigonelline, proline betaine, N-trimethyllysine were metabolites...
8.
Servillo L, DOnofrio N, Casale R, Cautela D, Giovane A, Castaldo D, et al.
Free Radic Biol Med . 2017 Mar; 108:8-18. PMID: 28300670
Ergothioneine (Egt), 2-mercapto-L-histidine betaine (ESH), is a dietary component acting as antioxidant and cytoprotectant. In vitro studies demonstrated that Egt, a powerful scavenger of hydroxyl radicals, superoxide anion, hypochlorous acid...
9.
Servillo L, Castaldo D, Giovane A, Casale R, DOnofrio N, Cautela D, et al.
J Agric Food Chem . 2017 Jan; 65(4):892-899. PMID: 28117581
Glucosylated forms of tyramine and some of its N-methylated derivatives are here reported for the first time to occur in Citrus genus plants. The compounds tyramine-O-β-d-glucoside, N-methyltyramine-O-β-d-glucoside, and N,N-dimethyltyramine-O-β-d-glucoside were...
10.
DOnofrio N, Servillo L, Giovane A, Casale R, Vitiello M, Marfella R, et al.
Free Radic Biol Med . 2016 Apr; 96:211-22. PMID: 27101740
Ergothioneine (Egt), the betaine of 2-mercapto-L-histidine, is a dietary antioxidant protecting against many diseases, including cardiovascular disease (CVD), through a redox mechanism different from alkylthiols. Here, experiments were designed to...