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Nunzia DOnofrio

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Articles 82
Citations 2149
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Recent Articles
1.
Donisi I, Colloca A, Anastasio C, Balestrieri M, DOnofrio N
Int J Biol Sci . 2024 Nov; 20(14):5779-5792. PMID: 39494332
The escalation of plastic pollution represents a global environmental and health problem. Important toxic effects have been attributed to the increasing diffusion of microplastics (MPs) and nanoplastics (NPs) derived from...
2.
Anastasio C, Donisi I, Del Vecchio V, Colloca A, Mele L, Sardu C, et al.
Cell Mol Biol Lett . 2024 May; 29(1):80. PMID: 38811901
Background: Sodium-glucose transporter 2 (SGLT2) inhibitors (iSGLT2) are approved medications for type 2 diabetes. Recent studies indicate that iSGLT2 inhibit the growth of some cancer cells. However, the mechanism(s) remains...
3.
Anastasio C, Donisi I, Colloca A, DOnofrio N, Balestrieri M
Int J Mol Sci . 2024 May; 25(10). PMID: 38791128
In endothelial cells, miR-148a-3p is involved in several pathological pathways, including chronic inflammatory conditions. However, the molecular mechanism of miR-148a-3p in endothelial inflammatory states is, to date, not fully elucidated....
4.
Colloca A, Donisi I, Anastasio C, Balestrieri M, DOnofrio N
Cells . 2024 Apr; 13(8. PMID: 38667278
Prediabetes and colorectal cancer (CRC) represent compelling health burdens responsible for high mortality and morbidity rates, sharing several modifiable risk factors. It has been hypothesized that metabolic abnormalities linking prediabetes...
5.
Marfella R, Prattichizzo F, Sardu C, Fulgenzi G, Graciotti L, Spadoni T, et al.
N Engl J Med . 2024 Mar; 390(10):900-910. PMID: 38446676
Background: Microplastics and nanoplastics (MNPs) are emerging as a potential risk factor for cardiovascular disease in preclinical studies. Direct evidence that this risk extends to humans is lacking. Methods: We...
6.
Martino E, DOnofrio N, Balestrieri A, Colloca A, Anastasio C, Sardu C, et al.
Nutrients . 2024 Jan; 16(1). PMID: 38201989
In the context of nutrient-driven epigenetic alterations, food-derived miRNAs can be absorbed into the circulatory system and organs of recipients, especially humans, and potentially contribute to modulating health and diseases....
7.
Cacciola N, Venneri T, Salzano A, DOnofrio N, Martano M, Saggese A, et al.
Cell Commun Signal . 2023 Sep; 21(1):245. PMID: 37730576
Background: Several studies show that natural foods are a source of compounds with anticancer properties that affect the gut microbiota and its metabolites. In the present study, we investigate the...
8.
Martino E, Balestrieri A, Aragona F, Bifulco G, Mele L, Campanile G, et al.
Cancers (Basel) . 2023 Sep; 15(17). PMID: 37686618
Ferroptosis, an iron-dependent form of cell death, and dysregulated microRNA (miRNA) expression correlate with colorectal cancer (CRC) development and progression. The tumor suppressor ability of miR-148a-3p has been reported for...
9.
Martino E, DOnofrio N, Balestrieri A, Mele L, Sardu C, Marfella R, et al.
Cell Mol Biol Lett . 2023 Aug; 28(1):66. PMID: 37587410
Background: Endothelial dysfunction and deregulated microRNAs (miRNAs) participate in the development of sepsis and are associated with septic organ failure and death. Here, we explored the role of miR-15b-5p on...
10.
Marfella R, Prattichizzo F, Sardu C, Paolisso P, DOnofrio N, Scisciola L, et al.
Atherosclerosis . 2023 Jul; 378:117180. PMID: 37422356
Background And Aims: Preclinical evidence suggests that proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors hold anti-inflammatory properties independently of their ability to lower LDL-cholesterol (C). However, whether PCSK9 inhibitors exert...