Rongbao Zhao
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Explore the profile of Rongbao Zhao including associated specialties, affiliations and a list of published articles.
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66
Citations
2343
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Recent Articles
1.
Ramachandra N, Vegivinti C, Sahu S, Sanawar R, Rivera-Pena B, Aminov S, et al.
Leuk Lymphoma
. 2024 Dec;
:1-10.
PMID: 39727008
Overactivation of the Transforming Growth Factor Beta (TGF-β) pathway is implicated in the pathogenesis of cytopenias in Myelodysplastic syndromes (MDS) and Acute Myeloid Leukemia (AML). IOA-359 and IOA-360 are potent...
2.
Vegivinti C, Keesari P, Veeraballi S, Martins Maia C, Mehta A, Lavu R, et al.
Exp Hematol Oncol
. 2023 Jul;
12(1):60.
PMID: 37422676
Dysregulation of the innate immune system and inflammatory-related pathways has been implicated in hematopoietic defects in the bone marrow microenvironment and associated with aging, clonal hematopoiesis, myelodysplastic syndromes (MDS), and...
3.
Zhan H, Najmi M, Lin K, Aluri S, Fiser A, Goldman I, et al.
J Biol Chem
. 2020 Sep;
295(46):15650-15661.
PMID: 32893190
The proton-coupled folate transporter (PCFT, SLC46A1) is required for folate intestinal absorption and transport across the choroid plexus. Recent work has identified a F392V mutation causing hereditary folate malabsorption. However,...
4.
Aluri S, Zhao R, Lin K, Shin D, Fiser A, Goldman I
J Biol Chem
. 2019 Mar;
294(18):7245-7258.
PMID: 30858177
The proton-coupled folate transporter (PCFT) mediates intestinal absorption of folates and their transport from blood to cerebrospinal fluid across the choroid plexus. Substitutions at Asp-109 in the first intracellular loop...
5.
Aluri S, Zhao R, Lubout C, Goorden S, Fiser A, Goldman I
Blood Adv
. 2018 Jan;
2(1):61-68.
PMID: 29344585
Hereditary folate malabsorption (HFM) is an autosomal recessive disorder characterized by impaired intestinal folate absorption and impaired folate transport across the choroid plexus due to loss of function of the...
6.
Zhao R, Najmi M, Aluri S, Spray D, Goldman I
Mol Pharmacol
. 2018 Jan;
93(3):208-215.
PMID: 29326243
The proton-coupled folate transporter (PCFT) is ubiquitously expressed in solid tumors to which it delivers antifolates, particularly pemetrexed, into cancer cells. Studies of PCFT-mediated transport, to date, have focused exclusively...
7.
Aluri S, Zhao R, Fiser A, Goldman I
Am J Physiol Cell Physiol
. 2017 Nov;
314(3):C289-C296.
PMID: 29167151
The proton-coupled folate transporter (PCFT-SLC46A1) is required for folate transport across the apical membrane of the small intestine and across the choroid plexus. This study focuses on the structure/function of...
8.
Aluri S, Zhao R, Fiser A, Goldman I
Biochim Biophys Acta Biomembr
. 2017 Aug;
1859(11):2193-2202.
PMID: 28802835
The proton-coupled folate transporter (PCFT-SLC46A1) is required for intestinal folate absorption and folate transport across the choroid plexus. This report addresses the structure/function of the 8th transmembrane helix. Based upon...
9.
Zhao R, Najmi M, Aluri S, Goldman I
Am J Physiol Cell Physiol
. 2017 Jan;
312(4):C517-C526.
PMID: 28122733
The substituted cysteine accessibility method (SCAM) is widely used to study the structure and function of channels, receptors and transporters. In its usual application, a cysteine residue is introduced into...
10.
Zhao R, Aluri S, Goldman I
Mol Aspects Med
. 2016 Sep;
53:57-72.
PMID: 27664775
The proton-coupled folate transporter (PCFT-SLC46A1) is the mechanism by which folates are absorbed across the brush-border membrane of the small intestine. The transporter is also expressed in the choroid plexus...