Ronald T Hay
Overview
Explore the profile of Ronald T Hay including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
126
Citations
7289
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Crowe C, Nakasone M, Chandler S, Craigon C, Sathe G, Tatham M, et al.
Sci Adv
. 2024 Oct;
10(41):eado6492.
PMID: 39392888
Small-molecule degraders of disease-driving proteins offer a clinically proven modality with enhanced therapeutic efficacy and potential to tackle previously undrugged targets. Stable and long-lived degrader-mediated ternary complexes drive fast and...
2.
Liu J, Ackermann L, Hoffmann S, Gal Z, Hendriks I, Jain C, et al.
Nat Struct Mol Biol
. 2024 Apr;
31(9):1355-1367.
PMID: 38649616
Protein SUMOylation provides a principal driving force for cellular stress responses, including DNA-protein crosslink (DPC) repair and arsenic-induced PML body degradation. In this study, using genome-scale screens, we identified the...
3.
Ip W, Tatham M, Krohne S, Gruhne J, Melling M, Meyer T, et al.
J Virol
. 2023 Nov;
97(11):e0079123.
PMID: 37916833
Human adenoviruses (HAdVs) generally cause mild and self-limiting diseases of the upper respiratory and gastrointestinal tracts but pose a serious risk to immunocompromised patients and children. Moreover, they are widely...
4.
Liczmanska M, Tatham M, Mojsa B, Eugui-Anta A, Rojas-Fernandez A, Ibrahim A, et al.
Cell Rep
. 2023 Aug;
42(8):112960.
PMID: 37556322
The small ubiquitin-like modifier (SUMO) protease SENP6 disassembles SUMO chains from cellular substrate proteins. We use a proteomic method to identify putative SENP6 substrates based on increased apparent molecular weight...
5.
Hertz E, Vega I, Kruse T, Wang Y, Hendriks I, Bizard A, et al.
Nat Struct Mol Biol
. 2023 Jul;
30(9):1303-1313.
PMID: 37474739
SUMOylation regulates numerous cellular processes, but what represents the essential functions of this protein modification remains unclear. To address this, we performed genome-scale CRISPR-Cas9-based screens, revealing that the BLM-TOP3A-RMI1-RMI2 (BTRR)-PICH...
6.
De La Cruz-Herrera C, Tatham M, Siddiqi U, Shire K, Marcon E, Greenblatt J, et al.
PLoS Pathog
. 2023 Jul;
19(7):e1011477.
PMID: 37410772
SUMO modifications regulate the function of many proteins and are important in controlling herpesvirus infections. We performed a site-specific proteomic analysis of SUMO1- and SUMO2-modified proteins in Epstein-Barr virus (EBV)...
7.
Jaffray E, Tatham M, Mojsa B, Liczmanska M, Rojas-Fernandez A, Yin Y, et al.
J Cell Biol
. 2023 Mar;
222(4).
PMID: 36880596
Acute Promyelocytic Leukemia is caused by expression of the oncogenic Promyelocytic Leukemia (PML)-Retinoic Acid Receptor Alpha (RARA) fusion protein. Therapy with arsenic trioxide results in degradation of PML-RARA and PML...
8.
Pelisch F, Sonneville R, Pourkarimi E, Agostinho A, Blow J, Gartner A, et al.
Nat Commun
. 2022 Nov;
13(1):7220.
PMID: 36434009
No abstract available.
9.
Vargas G, Cortes O, Arias-Munoz E, Hernandez S, Cerda-Troncoso C, Hernandez L, et al.
Front Cell Dev Biol
. 2022 Mar;
10:743287.
PMID: 35309917
Macroautophagy and the ubiquitin proteasome system work as an interconnected network in the maintenance of cellular homeostasis. Indeed, efficient activation of macroautophagy upon nutritional deprivation is sustained by degradation of...
10.
Mojsa B, Tatham M, Davidson L, Liczmanska M, Branigan E, Hay R
Mol Cell Proteomics
. 2021 Oct;
20:100164.
PMID: 34673284
To investigate the role of SUMO modification in the maintenance of pluripotent stem cells, we used ML792, a potent and selective inhibitor of SUMO Activating Enzyme. Treatment of human induced...