Ronald L Neppl
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Explore the profile of Ronald L Neppl including associated specialties, affiliations and a list of published articles.
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21
Citations
413
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Recent Articles
1.
Lee E, Charles J, Sinha I, Neppl R
Adv Biol (Weinh)
. 2024 May;
8(7):e2400152.
PMID: 38797891
Heterogeneous nuclear ribonucleoprotein U (hnRNPU) is known to play multiple biological roles by regulating transcriptional expression, RNA splicing, RNA stability, and chromatin structure in a tissue-dependent manner. The role of...
2.
Endo Y, Hwang C, Zhang Y, Olumi S, Koh D, Zhu C, et al.
Adv Biol (Weinh)
. 2023 Mar;
7(10):e2200320.
PMID: 36988414
Aging is associated with loss of skeletal muscle regeneration. Differentially regulated vascular endothelial growth factor (VEGF)A with aging may partially underlies this loss of regenerative capacity. To assess the role...
3.
Endo Y, Zhang Y, Olumi S, Karvar M, Argawal S, Neppl R, et al.
Genomics
. 2021 Jul;
113(5):2965-2976.
PMID: 34214629
Exercise is believed to be beneficial for skeletal muscle functions across all ages. Regimented exercise is often prescribed as an effective treatment/prophylaxis for age-related loss of muscle mass and function,...
4.
Lee E, Neppl R
Genes (Basel)
. 2021 Jun;
12(5).
PMID: 34063658
Skeletal muscle atrophy in an inevitable occurrence with advancing age, and a consequence of disease including cancer. Muscle atrophy in the elderly is managed by a regimen of resistance exercise...
5.
Endo Y, Baldino K, Li B, Zhang Y, Sakthivel D, MacArthur M, et al.
FASEB J
. 2020 Oct;
34(12):16086-16104.
PMID: 33064329
The ability of skeletal muscle to regenerate declines significantly with aging. The expression of aryl hydrocarbon receptor nuclear translocator (ARNT), a critical component of the hypoxia signaling pathway, was less...
6.
Bagchi D, Mason B, Baldino K, Li B, Lee E, Zhang Y, et al.
iScience
. 2020 Jul;
23(7):101319.
PMID: 32659719
Skeletal muscle has the remarkable ability to modulate its mass in response to changes in nutritional input, functional utilization, systemic disease, and age. This is achieved by the coordination of...
7.
Panayi A, Smit L, Hays N, Udeh K, Endo Y, Li B, et al.
Wound Repair Regen
. 2019 Oct;
28(1):61-74.
PMID: 31603580
Volumetric muscle loss (VML) is a segmental loss of skeletal muscle which commonly heals with fibrosis, minimal muscle regeneration, and loss of muscle strength. Treatment options for these wounds which...
8.
Guadagnin E, Bagchi D, Sinha I, Neppl R
Biochem Biophys Res Commun
. 2018 Dec;
508(3):838-843.
PMID: 30528731
Skeletal muscle regeneration following injury is a complex multi-stage process involving the recruitment of inflammatory cells, the activation of muscle resident fibroblasts, and the differentiation of activated myoblasts into myocytes....
9.
Neppl R, Wu C, Walsh K
J Cell Biol
. 2017 Sep;
216(11):3497-3507.
PMID: 28855249
Skeletal muscle exhibits remarkable plasticity in its ability to modulate its mass in response to the physiologic changes associated with functional use, systemic disease, and aging. Although a gradual loss...
10.
Neppl R, Wang D
Genes Dis
. 2014 Oct;
1(1):18-39.
PMID: 25328909
According to the World Health Organization, cardiovascular disease accounts for approximately 30% of all deaths in the United States, and is the worldwide leading cause of morbidity and mortality. Over...