Ronald C Conaway
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Explore the profile of Ronald C Conaway including associated specialties, affiliations and a list of published articles.
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102
Citations
6709
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Recent Articles
11.
Noe Gonzalez M, Conaway J, Conaway R
J Vis Exp
. 2019 May;
(147).
PMID: 31132066
Eukaryotic mRNA synthesis is a complex biochemical process requiring transcription of a DNA template into a precursor RNA by the multi-subunit enzyme RNA polymerase II and co-transcriptional capping and splicing...
12.
Wang L, He Y, Li M, Ding J, Sui Y, Conaway J, et al.
Protein Cell
. 2019 May;
10(9):694-699.
PMID: 31111444
No abstract available.
13.
Weems J, Unruh J, Slaughter B, Conaway R, Conaway J
Methods
. 2019 Feb;
159-160:157-164.
PMID: 30794906
Elongin A binds to Elongins B and C to form the RNA polymerase II transcription elongation factor Elongin. It also functions as the substrate recognition subunit of a ubiquitin ligase...
14.
Noe Gonzalez M, Conaway R, Conaway J
Mol Cell
. 2018 Dec;
72(5):802-804.
PMID: 30526870
In a recent publication in Science, Kujirai et al. (2018) use single-particle cryo-EM to resolve several Pol II-nucleosome interactions, shedding new light on transcription elongation in a native chromatin environment.
15.
Noe Gonzalez M, Sato S, Tomomori-Sato C, Conaway J, Conaway R
Nat Commun
. 2018 Aug;
9(1):3392.
PMID: 30139934
Co-transcriptional capping of RNA polymerase II (Pol II) transcripts by capping enzyme proceeds orders of magnitude more efficiently than capping of free RNA. Previous studies brought to light a role...
16.
Gopalan S, Gibbon D, Banks C, Zhang Y, Florens L, Washburn M, et al.
Nucleic Acids Res
. 2018 Aug;
46(19):10095-10105.
PMID: 30102332
ELL family transcription factors activate the overall rate of RNA polymerase II (Pol II) transcription elongation by binding directly to Pol II and suppressing its tendency to pause. In metazoa,...
17.
Conaway R
Annu Rev Biochem
. 2018 Jun;
87:23-25.
PMID: 29925254
Although cell metabolism has been established as a major regulator of eukaryotic gene expression, the mechanisms underlying this regulation are still being uncovered. Recent years have seen great advances in...
18.
Tsai K, Tomomori-Sato C, Sato S, Conaway R, Conaway J, Asturias F
Cell
. 2017 Sep;
158(2):463.
PMID: 28915369
No abstract available.
19.
Wu D, Zhao L, Feng Z, Yu C, Ding J, Wang L, et al.
J Biol Chem
. 2017 Apr;
292(24):10014-10025.
PMID: 28450392
The human males absent on the first (MOF)-containing histone acetyltransferase nonspecific lethal (NSL) complex comprises nine subunits including the -linked -acetylglucosamine (-GlcNAc) transferase, isoform 1 (OGT1). However, whether the -GlcNAc...
20.
Weems J, Slaughter B, Unruh J, Boeing S, Hall S, McLaird M, et al.
J Biol Chem
. 2017 Mar;
292(16):6431-6437.
PMID: 28292928
Elongin A performs dual functions as the transcriptionally active subunit of RNA polymerase II (Pol II) elongation factor Elongin and as the substrate recognition subunit of a Cullin-RING E3 ubiquitin...