Robin Krystufek
Overview
Explore the profile of Robin Krystufek including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
30
Followers
0
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Recent Articles
1.
Novotny P, Humpolickova J, Novakova V, Stanchev S, Strisovsky K, Zgarbova M, et al.
J Biol Chem
. 2024 Dec;
301(1):108079.
PMID: 39675720
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (M) autocatalytically releases itself out of the viral polyprotein to form a fully active mature dimer in a manner that is...
2.
Cermakova K, Simkova A, Wichterle F, Krystufek R, Stanurova J, Vanickova Z, et al.
Eur J Med Chem
. 2024 Oct;
280:116948.
PMID: 39437576
Fibroblast activation protein (FAP) has been extensively studied as a cancer biomarker for decades. Recently, small-molecule FAP inhibitors have been widely adopted as a targeting moiety of experimental theranostic radiotracers....
3.
Makarov M, Sanchez Rocha A, Krystufek R, Cherepashuk I, Dzmitruk V, Charnavets T, et al.
J Am Chem Soc
. 2023 Feb;
145(9):5320-5329.
PMID: 36826345
Whereas modern proteins rely on a quasi-universal repertoire of 20 canonical amino acids (AAs), numerous lines of evidence suggest that ancient proteins relied on a limited alphabet of 10 "early"...
4.
Krystufek R, Sacha P, Starkova J, Brynda J, Hradilek M, Tloustova E, et al.
J Med Chem
. 2021 May;
64(10):6706-6719.
PMID: 34006103
Cryptococcosis is an invasive infection that accounts for 15% of AIDS-related fatalities. Still, treating cryptococcosis remains a significant challenge due to the poor availability of effective antifungal therapies and emergence...
5.
Krystufek R, Sacha P
MethodsX
. 2019 Nov;
6:2230-2236.
PMID: 31667123
Advances in contactless acoustic liquid transfer technologies have unlocked opportunities to substantially increase the throughput of crystallization screens and decrease the consumption of reagents and consumables. Acoustic energy transfer enables...
6.
Krystufek R, Sacha P
J Immunol Methods
. 2019 Aug;
473:112640.
PMID: 31400409
The polyhistidine tag (His-tag) is one of the most commonly used epitope tags in protein engineering. While His-tagged proteins can be detected reliably using immunological methods such as ELISA and...
7.
Neburkova J, Sedlak F, Zackova Suchanova J, Kostka L, Sacha P, Subr V, et al.
Mol Pharm
. 2018 Feb;
15(8):2932-2945.
PMID: 29389139
Glutamate carboxypeptidase II (GCPII) is a membrane protease overexpressed by prostate cancer cells and detected in the neovasculature of most solid tumors. Targeting GCPII with inhibitor-bearing nanoparticles can enable recognition,...