Robert O Watson
Overview
Explore the profile of Robert O Watson including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
33
Citations
2085
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Weindel C, Martinez E, Zhao X, Mabry C, Bell S, Vail K, et al.
Cell
. 2022 Jul;
185(17):3214-3231.e23.
PMID: 35907404
Although mutations in mitochondrial-associated genes are linked to inflammation and susceptibility to infection, their mechanistic contributions to immune outcomes remain ill-defined. We discovered that the disease-associated gain-of-function allele Lrrk2 (leucine-rich...
12.
Cossu D, Watson R, Farina C
Front Immunol
. 2022 Jan;
12:816227.
PMID: 34975927
No abstract available.
13.
Vail K, da Silveira B, Bell S, Cohen N, Bordin A, Patrick K, et al.
PLoS Pathog
. 2021 Sep;
17(9):e1009888.
PMID: 34473814
Rhodococcus equi is a major cause of foal pneumonia and an opportunistic pathogen in immunocompromised humans. While alveolar macrophages constitute the primary replicative niche for R. equi, little is known...
14.
Wagner A, Scott H, West K, Vail K, Fitzsimons T, Coleman A, et al.
Front Immunol
. 2021 Jul;
12:656885.
PMID: 34305890
Pathogen sensing pattern recognition receptors triggers massive reprogramming of macrophage gene expression. While the signaling cascades and transcription factors that activate these responses are well-known, the role of post-transcriptional RNA...
15.
Bell S, Lopez K, Cox J, Patrick K, Watson R
mBio
. 2021 Jul;
12(4):e0187120.
PMID: 34225486
Mycobacterium tuberculosis (Mtb) causes one of the deadliest infectious diseases worldwide. Upon infection, Mtb is phagocytosed by macrophages and uses its virulence-associated ESX-1 secretion system to modulate the host cell....
16.
Lei Y, Martinez C, Torres-Odio S, Bell S, Birdwell C, Bryant J, et al.
Sci Adv
. 2021 May;
7(22).
PMID: 34039599
Mitochondrial dysfunction is a key driver of inflammatory responses in human disease. However, it remains unclear whether alterations in mitochondria-innate immune cross-talk contribute to the pathobiology of mitochondrial disorders and...
17.
Ding S, Yang J, Feng X, Pandey A, Barhoumi R, Zhang D, et al.
iScience
. 2021 Mar;
24(3):102192.
PMID: 33718841
Phagocytosis and autophagy play critical roles in immune defense. The human fungal pathogen (Cn) subverts host autophagy-initiation complex (AIC)-related proteins, to promote its phagocytosis and intracellular parasitism of host cells....
18.
Patrick K, Watson R
Infect Immun
. 2021 Feb;
89(4).
PMID: 33558322
Within the last decade, we have learned that damaged mitochondria activate many of the same innate immune pathways that evolved to sense and respond to intracellular pathogens. These shared responses...
19.
Hoffpauir C, Bell S, West K, Jing T, Wagner A, Torres-Odio S, et al.
J Immunol
. 2020 May;
205(1):153-167.
PMID: 32404352
Tripartite motif-containing proteins (TRIMs) play a variety of recently described roles in innate immunity. Although many TRIMs regulate type I IFN expression following cytosolic nucleic acid sensing of viruses, their...
20.
Weindel C, Bell S, Vail K, West K, Patrick K, Watson R
Elife
. 2020 Feb;
9.
PMID: 32057291
The Parkinson's disease (PD)-associated gene leucine-rich repeat kinase 2 () has been studied extensively in the brain. However, several studies have established that mutations in confer susceptibility to mycobacterial infection,...