Jeffery S Cox
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Explore the profile of Jeffery S Cox including associated specialties, affiliations and a list of published articles.
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70
Citations
8707
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Recent Articles
1.
Chin J, Abeydeera N, Repasy T, Rivera-Lugo R, Mitchell G, Nguyen V, et al.
bioRxiv
. 2025 Jan;
PMID: 39763950
Crosstalk between autophagy, host cell death, and inflammatory host responses to bacterial pathogens enables effective innate immune responses that limit bacterial growth while minimizing coincidental host damage. () thwarts innate...
2.
Golovkine G, Roberts A, Morrison H, Rivera-Lugo R, McCall R, Nilsson H, et al.
Nat Microbiol
. 2024 Feb;
9(7):1899.
PMID: 38308100
No abstract available.
3.
Mali S, Silva R, Gong Z, Cronce M, Vo U, Vuong C, et al.
bioRxiv
. 2024 Jan;
PMID: 38260476
SARS-CoV-2, the virus responsible for COVID-19, triggers symptoms such as sneezing, aches and pain. These symptoms are mediated by a subset of sensory neurons, known as nociceptors, that detect noxious...
4.
Morrison H, Craft J, Rivera-Lugo R, Johnson J, Golovkine G, Bell S, et al.
PLoS Pathog
. 2023 Jun;
19(6):e1011088.
PMID: 37352334
Macrophages employ an array of pattern recognition receptors to detect and eliminate intracellular pathogens that access the cytosol. The cytosolic carbohydrate sensors Galectin-3, -8, and -9 (Gal-3, Gal-8, and Gal-9)...
5.
Golovkine G, Roberts A, Morrison H, Rivera-Lugo R, McCall R, Nilsson H, et al.
Nat Microbiol
. 2023 Apr;
8(5):819-832.
PMID: 37037941
Whether or not autophagy has a role in defence against Mycobacterium tuberculosis infection remains unresolved. Previously, conditional knockdown of the core autophagy component ATG5 in myeloid cells was reported to...
6.
Van Dis E, Fox D, Morrison H, Fines D, Babirye J, McCann L, et al.
PLoS Pathog
. 2022 Jul;
18(7):e1010721.
PMID: 35877763
The prevailing model of protective immunity to tuberculosis is that CD4 T cells produce the cytokine IFN-γ to activate bactericidal mechanisms in infected macrophages. Although IFN-γ-independent CD4 T cell based...
7.
Perier C, Nasinghe E, Charles I, Ssetaba L, Ahyong V, Bangs D, et al.
Glob Health Action
. 2022 Jun;
15(1):2062175.
PMID: 35730550
Science education and research have the potential to drive profound change in low- and middle-income countries (LMICs) through encouraging innovation, attracting industry, and creating job opportunities. However, in LMICs, research...
8.
Johnson J, Crosby D, Hultquist J, Kurland A, Adhikary P, Li D, et al.
Cell Rep
. 2022 Apr;
39(2):110690.
PMID: 35417684
Viruses must effectively remodel host cellular pathways to replicate and evade immune defenses, and they must do so with limited genomic coding capacity. Targeting post-translational modification (PTM) pathways provides a...
9.
Mitchell G, Silvis M, Talkington K, Budzik J, Dodd C, Paluba J, et al.
mBio
. 2022 Jan;
13(1):e0272621.
PMID: 35073755
Ceragenins are a family of synthetic amphipathic molecules designed to mimic the properties of naturally occurring cationic antimicrobial peptides (CAMPs). Although ceragenins have potent antimicrobial activity, whether their mode of...
10.
Bell S, Lopez K, Cox J, Patrick K, Watson R
mBio
. 2021 Jul;
12(4):e0187120.
PMID: 34225486
Mycobacterium tuberculosis (Mtb) causes one of the deadliest infectious diseases worldwide. Upon infection, Mtb is phagocytosed by macrophages and uses its virulence-associated ESX-1 secretion system to modulate the host cell....