Robert J Vanner
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Explore the profile of Robert J Vanner including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
665
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Recent Articles
1.
Buttigieg M, Vlasschaert C, Bick A, Vanner R, Rauh M
Cell Rep Med
. 2025 Mar;
:101989.
PMID: 40037357
Clonal hematopoiesis (CH)-the expansion of somatically mutated hematopoietic cells-is common in solid cancers. CH is associated with systemic inflammation, but its impact on tumor biology is underexplored. Here, we report...
2.
Desai K, Wanggou S, Luis E, Whetstone H, Yu C, Vanner R, et al.
Nat Commun
. 2025 Feb;
16(1):1092.
PMID: 39904987
Functional cellular heterogeneity in tumours often underlies incomplete response to therapy and relapse. Previously, we demonstrated that the growth of the paediatric brain malignancy, sonic hedgehog subgroup medulloblastoma, is rooted...
3.
Calvillo-Arguelles O, Vanner R
JACC CardioOncol
. 2025 Feb;
7(1):34-37.
PMID: 39896119
No abstract available.
4.
Krishnan T, Solar Vasconcelos J, Titmuss E, Vanner R, Schaeffer D, Karsan A, et al.
Cancer Res Commun
. 2024 Dec;
5(1):66-73.
PMID: 39636207
Liquid biopsy is increasingly being used in oncology for tumor molecular characterization. CHIP is a common incidental finding in cfDNA, and its prevalence increases with age. This study builds on...
5.
Vanner R, Dobson S, Gan O, McLeod J, Schoof E, Grandal I, et al.
Blood Cancer Discov
. 2022 Jan;
3(1):16-31.
PMID: 35019858
Central nervous system (CNS) dissemination of B-precursor acute lymphoblastic leukemia (B-ALL) has poor prognosis and remains a therapeutic challenge. Here we performed targeted DNA sequencing as well as transcriptional and...
6.
Selvadurai H, Luis E, Desai K, Lan X, Vladoiu M, Whitley O, et al.
Cell Rep
. 2020 Apr;
31(2):107511.
PMID: 32294450
Medulloblastoma (MB) is a neoplasm linked to dysregulated cerebellar development. Previously, we demonstrated that the Sonic Hedgehog (SHH) subgroup grows hierarchically, with Sox2 cells at the apex of tumor progression...
7.
Dobson S, Garcia-Prat L, Vanner R, Wintersinger J, Waanders E, Gu Z, et al.
Cancer Discov
. 2020 Feb;
10(4):568-587.
PMID: 32086311
Disease recurrence causes significant mortality in B-progenitor acute lymphoblastic leukemia (B-ALL). Genomic analysis of matched diagnosis and relapse samples shows relapse often arising from minor diagnosis subclones. However, why therapy...
8.
Park N, Guilhamon P, Desai K, McAdam R, Langille E, OConnor M, et al.
Cell Stem Cell
. 2017 Sep;
21(3):411.
PMID: 28886368
No abstract available.
9.
Lan X, Jorg D, Cavalli F, Richards L, Nguyen L, Vanner R, et al.
Nature
. 2017 Aug;
549(7671):227-232.
PMID: 28854171
Human glioblastomas harbour a subpopulation of glioblastoma stem cells that drive tumorigenesis. However, the origin of intratumoural functional heterogeneity between glioblastoma cells remains poorly understood. Here we study the clonal...
10.
Park N, Guilhamon P, Desai K, McAdam R, Langille E, OConnor M, et al.
Cell Stem Cell
. 2017 Jul;
21(2):209-224.e7.
PMID: 28712938
Glioblastomas exhibit a hierarchical cellular organization, suggesting that they are driven by neoplastic stem cells that retain partial yet abnormal differentiation potential. Here, we show that a large subset of...