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Robert C Huebert

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Articles 55
Citations 1274
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Recent Articles
1.
Anwar A, Jalan-Sakrikar N, Huebert R
Semin Liver Dis . 2024 Nov; PMID: 39603269
The field of ribonucleic acid (RNA) biology has revealed an array of noncoding RNA species, particularly long noncoding RNAs (lncRNAs), which play crucial roles in liver disease pathogenesis. This review...
2.
Aseem S, Way G, Wang J, Zhao D, Tai Y, Gurley E, et al.
bioRxiv . 2024 Nov; PMID: 39574583
Background: Fibroinflammatory cholangiopathies, such as primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC), are characterized by inflammation and biliary fibrosis, driving disease-related complications. In biliary fibrosis, cholangiocytes activated by...
3.
Jalan-Sakrikar N, Guicciardi M, OHara S, Azad A, LaRusso N, Gores G, et al.
Hepatology . 2024 Sep; PMID: 39250501
Cholangiopathies comprise a spectrum of chronic intrahepatic and extrahepatic biliary tract disorders culminating in progressive cholestatic liver injury, fibrosis, and often cirrhosis and its sequela. Treatment for these diseases is...
4.
Khanal S, Liu Y, Bamidele A, Wixom A, Washington A, Jalan-Sakrikar N, et al.
Sci Adv . 2024 Jun; 10(26):eadn5228. PMID: 38941469
Liver fibrosis is characterized by the activation of perivascular hepatic stellate cells (HSCs), the release of fibrogenic nanosized extracellular vesicles (EVs), and increased HSC glycolysis. Nevertheless, how glycolysis in HSCs...
5.
Felgendreff P, Hosseiniasl S, Minshew A, Amiot B, Wilken S, Ahmadzada B, et al.
Biomedicines . 2024 Jun; 12(6). PMID: 38927479
In this study, a mixed porcine-human bioengineered liver (MPH-BEL) was used in a preclinical setup of extracorporeal liver support devices as a treatment for a model of post-resection liver failure...
6.
Jalan-Sakrikar N, Anwar A, Yaqoob U, Gan C, Lagnado A, Wixom A, et al.
JCI Insight . 2023 Sep; 8(20. PMID: 37707950
Cellular senescence and biliary fibrosis are prototypical features of obliterative cholangiopathies, such as primary sclerosing cholangitis (PSC). Telomere dysfunction can lead to senescence either through telomere erosion or damaged telomeres....
7.
Hosseiniasl S, Felgendreff P, Tharwat M, Amiot B, AbuRmilah A, Minshew A, et al.
Cytotherapy . 2023 Feb; 25(5):483-489. PMID: 36842850
Background Aims: Roux en y anastomosis is a preferred method of biliary reconstruction in liver transplantation that involves living donors or pediatric patients. However, biliary stricture is a frequent and...
8.
Jalan-Sakrikar N, Brevini T, Huebert R, Sampaziotis F
Hepatology . 2022 May; 77(1):305-322. PMID: 35596930
The burden of liver diseases is increasing worldwide, with liver transplantation remaining the only treatment option for end-stage liver disease. Regenerative medicine holds great potential as a therapeutic alternative, aiming...
9.
Feighery A, Aseem S, Huebert R
Mayo Clin Proc . 2022 Mar; 97(4):795-800. PMID: 35287955
No abstract available.
10.
Yetmar Z, Ranganath N, Huebert R, Rosen C, Razonable R, Beam E
Transplantation . 2022 Jan; 106(3):e181-e182. PMID: 34974450
No abstract available.