Robert Blackwell
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Explore the profile of Robert Blackwell including associated specialties, affiliations and a list of published articles.
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18
Citations
272
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Recent Articles
1.
Ojha A, Blackwell R, Cruz-Chu E, Dsouza R, Astore M, Schwander P, et al.
Acta Crystallogr D Struct Biol
. 2025 Feb;
81(Pt 3):89-104.
PMID: 40019002
Resolving continuous conformational heterogeneity in single-particle cryo-electron microscopy (cryo-EM) is a field in which new methods are now emerging regularly. Methods range from traditional statistical techniques to state-of-the-art neural network...
2.
Hamamsy T, Morton J, Blackwell R, Berenberg D, Carriero N, Gligorijevic V, et al.
Nat Biotechnol
. 2023 Sep;
42(6):975-985.
PMID: 37679542
Exploiting sequence-structure-function relationships in biotechnology requires improved methods for aligning proteins that have low sequence similarity to previously annotated proteins. We develop two deep learning methods to address this gap,...
3.
Dutta S, Farhadifar R, Lu W, Kabacaoglu G, Blackwell R, Stein D, et al.
bioRxiv
. 2023 Apr;
PMID: 37066165
Life in complex systems, such as cities and organisms, comes to a standstill when global coordination of mass, energy, and information flows is disrupted. Global coordination is no less important...
4.
Dutta S, Farhadifar R, Lu W, Kabacaoglu G, Blackwell R, Stein D, et al.
ArXiv
. 2023 Apr;
PMID: 37064529
Life in complex systems, such as cities and organisms, comes to a standstill when global coordination of mass, energy, and information flows is disrupted. Global coordination is no less important...
5.
Yan W, Ansari S, Lamson A, Glaser M, Blackwell R, Betterton M, et al.
Elife
. 2022 May;
11.
PMID: 35617115
The cytoskeleton - a collection of polymeric filaments, molecular motors, and crosslinkers - is a foundational example of active matter, and in the cell assembles into organelles that guide basic...
6.
Blackwell R, Hemmerle A, Baer A, Spath M, Peukert W, Parsons D, et al.
J Colloid Interface Sci
. 2021 May;
598:464-473.
PMID: 33951546
Hypothesis: Interaction of cellular membranes with biointerfaces is of vital importance for a number of medical devices and implants. Adhesiveness of these surfaces and cells is often regulated by depositing...
7.
Edelmaier C, Lamson A, Gergely Z, Ansari S, Blackwell R, McIntosh J, et al.
Elife
. 2020 Feb;
9.
PMID: 32053104
The essential functions required for mitotic spindle assembly and chromosome biorientation and segregation are not fully understood, despite extensive study. To illuminate the combinations of ingredients most important to align...
8.
AlTurki A, Marafi M, Proietti R, Cardinale D, Blackwell R, Dorian P, et al.
Circ Arrhythm Electrophysiol
. 2020 Jan;
13(1):e007437.
PMID: 31944855
Background: Postoperative atrial fibrillation (POAF) is a frequent occurrence after noncardiac surgery. It remains unclear whether POAF is associated with an increased risk of major adverse events. We aimed to...
9.
Janes J, Schmidt D, Blackwell R, Seifert U, Smith A
Biophys J
. 2019 Jul;
117(3):542-552.
PMID: 31349987
In biological settings, membranes typically interact locally with other membranes: the extracellular matrix in the exterior or internal cellular structures such as the cytoskeleton, locally pinning the membrane. Characterizing the...
10.
Rincon S, Lamson A, Blackwell R, Syrovatkina V, Fraisier V, Paoletti A, et al.
Nat Commun
. 2017 May;
8:15286.
PMID: 28513584
Bipolar spindle assembly requires a balance of forces where kinesin-5 produces outward pushing forces to antagonize the inward pulling forces from kinesin-14 or dynein. Accordingly, Kinesin-5 inactivation results in force...