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Michael J Shelley

Explore the profile of Michael J Shelley including associated specialties, affiliations and a list of published articles. Areas
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Articles 57
Citations 661
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Recent Articles
1.
Weady S, Palmer B, Lamson A, Kim T, Farhadifar R, Shelley M
Phys Rev Lett . 2024 Oct; 133(15):158402. PMID: 39454152
We study the dynamics of proliferating cell collectives whose microscopic constituents' growth is inhibited by macroscopic growth-induced stress. Discrete particle simulations of a growing collective show the emergence of concentric-ring...
2.
Chakrabarti B, Rachh M, Shvartsman S, Shelley M
Proc Natl Acad Sci U S A . 2024 Jul; 121(30):e2405114121. PMID: 39012825
Large cells often rely on cytoplasmic flows for intracellular transport, maintaining homeostasis, and positioning cellular components. Understanding the mechanisms of these flows is essential for gaining insights into cell function,...
3.
Anjur-Dietrich M, Gomez Hererra V, Farhadifar R, Wu H, Merta H, Bahmanyar S, et al.
Dev Cell . 2024 Jun; 59(18):2429-2442.e4. PMID: 38866013
The forces that orient the spindle in human cells remain poorly understood due to a lack of direct mechanical measurements in mammalian systems. We use magnetic tweezers to measure the...
4.
Stein D, Shelley M
Curr Opin Cell Biol . 2024 Jun; 89:102379. PMID: 38850680
Mathematical models are indispensable for disentangling the interactions through which biological components work together to generate the forces and flows that position, mix, and distribute proteins, nutrients, and organelles within...
5.
Ansari S, Yan W, Lamson A, Shelley M, Glaser M, Betterton M
Front Phys . 2023 Dec; 10. PMID: 38116396
Living systems exhibit self-organization, a phenomenon that enables organisms to perform functions essential for life. The interior of living cells is a crowded environment in which the self-assembly of cytoskeletal...
6.
Anjur-Dietrich M, Gomez Hererra V, Farhadifar R, Wu H, Merta H, Bahmanyar S, et al.
bioRxiv . 2023 Sep; PMID: 37745442
The forces which orient the spindle in human cells remain poorly understood due to a lack of direct mechanical measurements in mammalian systems. We use magnetic tweezers to measure the...
7.
Stone H, Shelley M, Boyko E
Soft Matter . 2023 Jul; 19(28):5353-5359. PMID: 37404018
We present a direct derivation of the typical time derivatives used in a continuum description of complex fluid flows, harnessing the principles of the kinematics of line elements. The evolution...
8.
Dutta S, Farhadifar R, Lu W, Kabacaoglu G, Blackwell R, Stein D, et al.
bioRxiv . 2023 Apr; PMID: 37066165
Life in complex systems, such as cities and organisms, comes to a standstill when global coordination of mass, energy, and information flows is disrupted. Global coordination is no less important...
9.
Dutta S, Farhadifar R, Lu W, Kabacaoglu G, Blackwell R, Stein D, et al.
ArXiv . 2023 Apr; PMID: 37064529
Life in complex systems, such as cities and organisms, comes to a standstill when global coordination of mass, energy, and information flows is disrupted. Global coordination is no less important...
10.
Chakrabarti B, Shelley M, Furthauer S
Phys Rev Lett . 2023 Apr; 130(12):128202. PMID: 37027863
Many active particles, such as swimming micro-organisms or motor proteins, do work on their environment by going though a periodic sequence of shapes. Interactions between particles can lead to synchronization...