Robert B Flint
Overview
Explore the profile of Robert B Flint including associated specialties, affiliations and a list of published articles.
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50
Citations
260
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Recent Articles
1.
Schouwenburg S, Preijers T, Flint R, Wildschut E, Koch B, de Winter B, et al.
J Infect Dis
. 2025 Feb;
PMID: 39903655
Objectives: In pediatric patients, vancomycin plays a pivotal role in combating infections, necessitating precise therapeutic drug monitoring to ensure efficacy and safety. The adoption of model-informed precision dosing (MIPD) has...
2.
Storm K, Flint R, Onland W, van Kaam A, Reiss I, Hutten G, et al.
Neonatology
. 2024 Dec;
1-12.
PMID: 39681093
Introduction: Caffeine is the registered pharmacologic treatment for apnea of prematurity and is extensively used in the neonatal intensive care units (NICUs) based on evidence from randomized controlled trials. This...
3.
Allegaert K, Yalcin N, Flint R, Simons S
Children (Basel)
. 2024 Sep;
11(9).
PMID: 39334634
Similar to other populations, care of neonates strongly relies on robust guidance on neonatal pharmacotherapy, covering an age-appropriate drug formulation, an individualized dose, and information on its efficacy and safety...
4.
Schouwenburg S, Keij F, Tramper-Stranders G, Kornelisse R, Reiss I, De Cock P, et al.
Clin Pharmacol Ther
. 2024 Aug;
117(1):193-202.
PMID: 39205386
Data published on the oral clavulanic acid pharmacokinetics in the pediatric population is lacking. This research aimed to describe clavulanic acid disposition following oral and intravenous administration and to provide...
5.
Ramlakhan K, Roos-Hesselink J, Basso T, Greenslade J, Flint R, Krieger E, et al.
Int J Cardiol
. 2024 Jun;
410:132234.
PMID: 38844094
Background: Beta-blockers are commonly used drugs during pregnancy, especially in women with heart disease, and are regarded as relatively safe although evidence is sparse. Differences between beta-blockers are not well-studied....
6.
Wu Y, Allegaert K, Flint R, Goulooze S, Valitalo P, de Hoog M, et al.
Pharm Res
. 2024 Mar;
41(4):637-649.
PMID: 38472610
Aims: Whether and when glomerular filtration rate (GFR) in preterms catches up with term peers is unknown. This study aims to develop a GFR maturation model for (pre)term-born individuals from...
7.
Bahmany S, Hassanzai M, Flint R, van Onzenoort H, de Winter B, Koch B
Clin Chim Acta
. 2023 Dec;
553:117689.
PMID: 38052384
Background: Vancomycin is a widely used antibiotic for the treatment of gram-positive bacterial infections, especially for methicillin-resistant Staphylococcus aureus (MRSA) infections. Due to a small therapeutic range and large inter-patient...
8.
Poppe J, Flint R, Smits A, Willemsen S, Storm K, Nuytemans D, et al.
Trials
. 2023 Oct;
24(1):656.
PMID: 37817255
Background: Apnoea of prematurity (AOP) is one of the most common diagnoses among preterm infants. AOP often leads to hypoxemia and bradycardia which are associated with an increased risk of...
9.
Keij F, Schouwenburg S, Kornelisse R, Preijers T, Mir F, Degraeuwe P, et al.
Clin Infect Dis
. 2023 Sep;
77(11):1595-1603.
PMID: 37757471
Background: There is a lack of evidence on oral amoxicillin pharmacokinetics and exposure in neonates with possible serious bacterial infection (pSBI). We aimed to describe amoxicillin disposition following oral and...
10.
Mahoney L, Raffaeli G, Beken S, Unal S, Kotidis C, Cavallaro G, et al.
Pediatr Res
. 2023 Sep;
95(1):75-83.
PMID: 37752246
Background: Many drugs are used off-label or unlicensed in neonates. This does not mean they are used without evidence or knowledge. We aimed to apply and evaluate the Grading and...