Aline G J Engbers
Overview
Explore the profile of Aline G J Engbers including associated specialties, affiliations and a list of published articles.
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8
Citations
45
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0
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Recent Articles
1.
Smit C, Engbers A, Samiee-Zafarghandy S, van Donge T, Simons S, Flint R, et al.
Neonatology
. 2022 Dec;
120(1):81-89.
PMID: 36502794
Introduction: Oral ibuprofen is more effective than intravenous (IV) ibuprofen for closure of a patent ductus arteriosus (PDA). This study explored whether higher concentrations of the biologically active S-enantiomer or...
2.
Engbers A, Voller S, Flint R, Goulooze S, de Klerk J, Krekels E, et al.
Clin Pharmacol Ther
. 2022 Apr;
112(2):307-315.
PMID: 35429165
Spontaneous closure of the ductus arteriosus depends on gestational age (GA) and might be delayed in preterm infants, resulting in patent ductus arteriosus (PDA). Ibuprofen can be administered to enhance...
3.
Engbers A, Flint R, Voeller S, Reiss I, Liem K, Alffenaar J, et al.
Arch Dis Child
. 2022 Jan;
107(4):400-406.
PMID: 35074829
Introduction: Fluconazole is an important antifungal in the prevention and treatment of invasive infections in neonates, even though its use in preterm infants is still off-label. Here, we performed a...
4.
Zwart T, de Vries A, Engbers A, Dam R, van der Boog P, Swen J, et al.
Clin Pharmacokinet
. 2021 Apr;
60(9):1201-1215.
PMID: 33864239
Background: Iohexol plasma clearance-based glomerular filtration rate (GFR) determination provides an accurate method for renal function evaluation. This technique is increasingly advocated for clinical situations that dictate highly accurate renal...
5.
Engbers A, Voller S, Poets C, Knibbe C, Reiss I, Koch B, et al.
Neonatology
. 2021 Feb;
118(1):106-113.
PMID: 33626528
Background: Apnea of prematurity can persist despite caffeine therapy in preterm infants. Doxapram may additionally support breathing. Although multiple small studies have reported the efficacy of doxapram, the structural co-treatment...
6.
de Klerk J, Engbers A, van Beek F, Flint R, Reiss I, Voller S, et al.
Front Pediatr
. 2020 Oct;
8:541.
PMID: 33014935
The optimal management strategy for patent ductus arteriosus in preterm infants remains a topic of debate. Available evidence for a treatment strategy might be biased by the delayed spontaneous closure...
7.
Flint R, Simons S, Andriessen P, Liem K, Degraeuwe P, Reiss I, et al.
Pediatr Res
. 2020 Jul;
89(5):1268-1277.
PMID: 32698193
Background: Doxapram is used for the treatment of apnea of prematurity in dosing regimens only based on bodyweight, as pharmacokinetic data are limited. This study describes the pharmacokinetics of doxapram...
8.
Engbers A, Flint R, Voller S, de Klerk J, Reiss I, Andriessen P, et al.
Br J Clin Pharmacol
. 2020 Apr;
86(10):2028-2039.
PMID: 32250464
Aims: Racemic ibuprofen is widely used for the treatment of preterm neonates with patent ductus arteriosus. Currently used bodyweight-based dosing guidelines are based on total ibuprofen, while only the S-enantiomer...