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Kian D Liem

Explore the profile of Kian D Liem including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 286
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Recent Articles
1.
Benavente-Fernandez I, Steggerda S, Liem K, Lubian-Lopez S, de Vries L
J Pediatr . 2023 Jun; 261:113578. PMID: 37353143
Objective: To study the potential role of ventricular volume (VV) estimation in the management of posthemorrhagic ventricular dilatation related to the need for ventriculoperitoneal (VP)-shunt insertion and 2-year neurodevelopmental outcome...
2.
Engbers A, Flint R, Voeller S, Reiss I, Liem K, Alffenaar J, et al.
Arch Dis Child . 2022 Jan; 107(4):400-406. PMID: 35074829
Introduction: Fluconazole is an important antifungal in the prevention and treatment of invasive infections in neonates, even though its use in preterm infants is still off-label. Here, we performed a...
3.
Bruckner M, Wolfsberger C, Dempsey E, Liem K, Lemmers P, Alderliesten T, et al.
Pediatr Res . 2021 Oct; 96(4):844-855. PMID: 34667270
Background: The aim of this systematic qualitative review was to give an overview of reference ranges defined as normal values or centile charts of regional tissue oxygen saturation measured by...
4.
Gan K, Oei J, Quah-Smith I, Kamar A, Lordudass A, Liem K, et al.
Front Pediatr . 2021 Jan; 8:615008. PMID: 33425820
Eye exam for Retinopathy of prematurity (ROP) is a painful procedure and pharmacological analgesia might be ineffective. We hypothesized that magnetic auricular acupuncture (MAA) compared to placebo will decrease pain...
5.
Cizmeci M, Groenendaal F, Liem K, van Haastert I, Benavente-Fernandez I, van Straaten H, et al.
J Pediatr . 2020 Aug; 226:28-35.e3. PMID: 32800815
Objective: To compare the effect of intervention at low vs high threshold of ventriculomegaly in preterm infants with posthemorrhagic ventricular dilatation on death or severe neurodevelopmental disability. Study Design: This...
6.
Flint R, Simons S, Andriessen P, Liem K, Degraeuwe P, Reiss I, et al.
Pediatr Res . 2020 Jul; 89(5):1268-1277. PMID: 32698193
Background: Doxapram is used for the treatment of apnea of prematurity in dosing regimens only based on bodyweight, as pharmacokinetic data are limited. This study describes the pharmacokinetics of doxapram...
7.
Engbers A, Flint R, Voller S, de Klerk J, Reiss I, Andriessen P, et al.
Br J Clin Pharmacol . 2020 Apr; 86(10):2028-2039. PMID: 32250464
Aims: Racemic ibuprofen is widely used for the treatment of preterm neonates with patent ductus arteriosus. Currently used bodyweight-based dosing guidelines are based on total ibuprofen, while only the S-enantiomer...
8.
Sprenkeler E, Henriet S, Tool A, Kreft I, van der Bijl I, Aarts C, et al.
Blood . 2020 Mar; 135(24):2171-2181. PMID: 32128589
Megakaryoblastic leukemia 1 (MKL1) promotes the regulation of essential cell processes, including actin cytoskeletal dynamics, by coactivating serum response factor. Recently, the first human with MKL1 deficiency, leading to a...
9.
Voller S, Flint R, Andriessen P, Allegaert K, Zimmermann L, Liem K, et al.
Arch Dis Child Fetal Neonatal Ed . 2019 Sep; 104(6):F598-F603. PMID: 31498775
Background: Fentanyl is frequently used off-label in preterm newborns. Due to very limited pharmacokinetic and pharmacodynamic data, fentanyl dosing is mostly based on bodyweight. This study describes the maturation of...
10.
Voller S, Flint R, Beggah F, Reiss I, Andriessen P, Zimmermann L, et al.
J Clin Pharmacol . 2019 May; 59(10):1300-1308. PMID: 31093992
Although midazolam is a frequently used sedative in neonatal intensive care units, its use in preterm neonates has been off-label. Recently, a new dosing advice for midazolam for sedation on...