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Rob W M Henderson

Explore the profile of Rob W M Henderson including associated specialties, affiliations and a list of published articles. Areas
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Citations 18
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Recent Articles
1.
Dechering K, Timmerman M, Rensen K, Koolen K, Honarnejad S, Vos M, et al.
SLAS Discov . 2022 Jul; 27(6):337-348. PMID: 35872229
A central challenge of antimalarial therapy is the emergence of resistance to the components of artemisinin-based combination therapies (ACTs) and the urgent need for new drugs acting through novel mechanism...
2.
de Vries L, Jansen P, Barcelo C, Munro J, Verhoef J, Pasaje C, et al.
Nat Commun . 2022 Apr; 13(1):2158. PMID: 35444200
Drug resistance and a dire lack of transmission-blocking antimalarials hamper malaria elimination. Here, we present the pantothenamide MMV693183 as a first-in-class acetyl-CoA synthetase (AcAS) inhibitor to enter preclinical development. Our...