Rizwan Hasan Khan
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Explore the profile of Rizwan Hasan Khan including associated specialties, affiliations and a list of published articles.
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Articles
289
Citations
2001
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Recent Articles
1.
Fatima M, Nabi F, Khan R, Naeem A
Spectrochim Acta A Mol Biomol Spectrosc
. 2025 Mar;
335:125953.
PMID: 40081302
Aggregation of proteins occurs because of improper protein folding and is responsible for the development of multiple severe maladies such as Type II diabetes mellitus, Parkison's, Huntington's, and spongiform encephalopathy....
2.
Hussain N, Khan M, Sharma A, Singh R, Khan R
Neurochem Int
. 2025 Feb;
184:105947.
PMID: 39956324
The interplay between immune cell dysfunction and associated neuroinflammation plays a critical role in the pathogenesis of Alzheimer's disease. Neuroinflammation, orchestrated by microglia and peripheral immune cells, exacerbates synaptic dysfunction...
3.
Hassan M, Hussain M, Khan R
Prog Mol Biol Transl Sci
. 2025 Feb;
211:145-168.
PMID: 39947747
One of the hallmarks of multiple neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases, is deposition of insoluble amyloid fibrils, which are toxic proteinaceous structures containing cross β-sheets. Several inhibitory...
4.
Ahmad Y, Nabi F, Siddiqui S, Khan R, Habib S, Moin S
Arch Biochem Biophys
. 2025 Jan;
766:110292.
PMID: 39793942
Glycation leads to the formation of protein aggregates and advanced glycation end products (AGEs) by non-enzymatic reaction. AGEs have been linked to several pathological conditions such as diabetes, cardiovascular disorders,...
5.
Alrouji M, Furkan M, Alnuaimi G, Yasmin S, Alhumaydhi F, Khan R, et al.
Int J Biol Macromol
. 2024 Dec;
289:138829.
PMID: 39694350
In recent times, neurodegenerative diseases (NDs), such as Alzheimer's disease (AD), Parkinson's disease (PD) and others, represent a major global health challenge with increasing prevalence and significant socio-economic impact. These...
6.
Nabi F, Ahmad O, Fatima A, Ahmad A, Sharma J, Khan R
J Biomol Struct Dyn
. 2024 Dec;
:1-13.
PMID: 39633599
Alzheimer's disease (AD) is a progressive and largely incurable neurodegenerative disorder that affects millions of people worldwide. It is characterised by the accumulation of amyloid-beta plaques and neurofibrillary tangles in...
7.
Hassan M, Ahmad A, Hussain M, Gupta S, Khan H, Aziz T, et al.
ACS Chem Neurosci
. 2024 Dec;
15(24):4517-4532.
PMID: 39628315
Neurodegenerative diseases, notably Alzheimer's and Parkinson's, hallmark their progression through the formation of amyloid aggregates resulting from misfolding. While current therapeutics alleviate symptoms, they do not impede disease onset. In...
8.
Shamsi A, Khan M, Yadav D, Shahwan M, Furkan M, Khan R
Sci Rep
. 2024 Sep;
14(1):21778.
PMID: 39294237
No abstract available.
9.
Shamsi A, Khan M, Yadav D, Shahwan M, Furkan M, Khan R
Sci Rep
. 2024 Aug;
14(1):19439.
PMID: 39169082
Developing new therapeutic strategies to target specific molecular pathways has become a primary focus in modern drug discovery science. Fibroblast growth factor receptor 2 (FGFR2) is a critical signaling protein...
10.
Shamsi A, Shahwan M, Furkan M, Yadav D, Khan R
Heliyon
. 2024 Jul;
10(13):e32755.
PMID: 39027624
The involvement of neuroinflammation in the pathogenesis of neurodegenerative disorders (NDs) is very significant. Currently, only symptomatic treatments exist, and there are no drugs that modify the progression of Alzheimer's...