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Mohammad Furkan

Explore the profile of Mohammad Furkan including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 78
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Recent Articles
1.
Alrouji M, Furkan M, Alnuaimi G, Yasmin S, Alhumaydhi F, Khan R, et al.
Int J Biol Macromol . 2024 Dec; 289:138829. PMID: 39694350
In recent times, neurodegenerative diseases (NDs), such as Alzheimer's disease (AD), Parkinson's disease (PD) and others, represent a major global health challenge with increasing prevalence and significant socio-economic impact. These...
2.
Shamsi A, Khan M, Yadav D, Shahwan M, Furkan M, Khan R
Sci Rep . 2024 Sep; 14(1):21778. PMID: 39294237
No abstract available.
3.
Shamsi A, Khan M, Yadav D, Shahwan M, Furkan M, Khan R
Sci Rep . 2024 Aug; 14(1):19439. PMID: 39169082
Developing new therapeutic strategies to target specific molecular pathways has become a primary focus in modern drug discovery science. Fibroblast growth factor receptor 2 (FGFR2) is a critical signaling protein...
4.
Shamsi A, Shahwan M, Furkan M, Yadav D, Khan R
Heliyon . 2024 Jul; 10(13):e32755. PMID: 39027624
The involvement of neuroinflammation in the pathogenesis of neurodegenerative disorders (NDs) is very significant. Currently, only symptomatic treatments exist, and there are no drugs that modify the progression of Alzheimer's...
5.
Shamsi A, Furkan M, Khan M, Yadav D, Shahwan M
J Alzheimers Dis . 2024 Jun; 100(2):475-485. PMID: 38875044
Background: HMGCS2 (mitochondrial 3-hydroxy-3-methylglutaryl-COA synthase 2) plays a pivotal role as a control enzyme in ketogenesis, and its association with the amyloid-β protein precursor (AβPP) in mitochondria implicates a potential...
6.
Alrouji M, Yasmin S, Alhumaydhi F, Sharaf S, Shahwan M, Furkan M, et al.
Front Pharmacol . 2024 May; 15:1397332. PMID: 38799161
In present times, vanillin stands out as a promising therapeutic molecule that can be implicated in the treatment of neurodegenerative disorders (NDs), notably Alzheimer's disease (AD). This can be attributed...
7.
Alrouji M, Yasmin S, Furkan M, Alhumaydhi F, Sharaf S, Khan R, et al.
J Alzheimers Dis . 2024 May; 99(1):333-343. PMID: 38701154
Background: Neurodegeneration is a term describing an irreversible process of neuronal damage. In recent decades, research efforts have been directed towards deepening our knowledge of numerous neurodegenerative disorders, with a...
8.
Alrouji M, Alhumaydhi F, Furkan M, Venkatesan K, Sharaf S, Shahwan M, et al.
ACS Omega . 2024 Apr; 9(14):16089-16096. PMID: 38617645
Human transferrin (Htf) is vital in maintaining iron within the brain cells; any disruption results in the development of neurodegenerative diseases (NDs) and other related pathologies, especially Alzheimer's disease (AD)....
9.
Qais F, Furkan M, Altaf M, Ahmad I, Khan R
Int J Biol Macromol . 2024 Apr; 267(Pt 1):131573. PMID: 38614188
DNA, vital for biological processes, encodes hereditary data for protein synthesis, shaping cell structure and function. Since revealing its structure, DNA has become a target for various therapeutically vital molecules,...
10.
Furkan M, Khan M, Shahwan M, Hassan N, Yadav D, Anwar S, et al.
Int J Biol Macromol . 2024 Jan; 259(Pt 2):129167. PMID: 38176507
Apolipoprotein E (ApoE), a pivotal contributor to lipid metabolism and neurodegenerative disorders, emerges as an attractive target for therapeutic intervention. Within this study, we deployed an integrated in-silico strategy, harnessing...