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Saima Nusrat

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Articles 29
Citations 140
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Zaman M, Safdari H, Khan A, Zakariya S, Nusrat S, Chandel T, et al.
J Biomol Struct Dyn . 2018 Nov; 37(16):4338-4344. PMID: 30488768
Communicated by Ramaswamy H. Sarma.
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Siddiqi M, Alam P, Iqbal T, Majid N, Malik S, Nusrat S, et al.
Front Chem . 2018 Aug; 6:311. PMID: 30123793
Inhibition of fibrillation process and disaggregation of mature fibrils using small peptide are the promising remedial strategies to combat neurodegenerative diseases. However, designing peptide-based drugs to target β-sheet-rich amyloid has...
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Siddiqi M, Alam P, Chaturvedi S, Khan M, Nusrat S, Malik S, et al.
Biochim Biophys Acta Proteins Proteom . 2018 Mar; 1866(4):549-557. PMID: 29496560
Protein aggregation and amyloid fibrillation are responsible for several serious pathological conditions (like type II diabetes, Alzheimer's and Parkinson's diseases etc.) and protein drugs ineffectiveness. Therefore, a molecule that can...
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Zaman M, Khan M, Zakariya S, Nusrat S, Meeran S, Alam P, et al.
J Cell Biochem . 2018 Jan; 119(5):3945-3956. PMID: 29350433
Protein misfolding and aggregation lead to amyloid generation that in turn may induce cell membrane disruption and leads to cell apoptosis. In an effort to prevent or treat amyloidogenesis, large...
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Nusrat S, Masroor A, Zaman M, Siddiqi M, Ajmal M, Zaidi N, et al.
Int J Biol Macromol . 2017 Nov; 109:1132-1139. PMID: 29157902
The current study comprises of an inclusive biophysical study, enlightening the binding of L-3, 4-dihydroxyphenylalanine (l-Dopa) with human lysozyme (HL) and hen egg white lysozyme (HEWL). Spectroscopic and molecular docking...
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Nusrat S, Khan R
Prep Biochem Biotechnol . 2017 Nov; 48(1):43-56. PMID: 29106330
The association of protein aggregates with plentiful human diseases has fascinated studies regarding the biophysical characterization of protein misfolding and ultimately their aggregate formation mechanism. Protein-ligand interaction, their mechanism, conformational...
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Ishtikhar M, Ahmad E, Siddiqui Z, Ahmad S, Khan M, Zaman M, et al.
Int J Biol Macromol . 2017 Nov; 107(Pt B):2450-2464. PMID: 29102789
Numerous phenolic compounds have been reported in the last decade that have a good antioxidant property and interaction affinity towards mammalian serum albumins. In the present study, we have utilized...
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Siddiqi M, Nusrat S, Alam P, Malik S, Chaturvedi S, Ajmal M, et al.
Int J Biol Macromol . 2017 Oct; 107(Pt B):1414-1421. PMID: 28987797
We have studied the binding of busulfan (BN) to human serum albumin (HSA) at physiological pH 7.4 by using fluorescence, UV-vis and circular dichroism (CD) spectroscopic tools, as well as...