Riko Nishimura
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Explore the profile of Riko Nishimura including associated specialties, affiliations and a list of published articles.
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89
Citations
3190
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Recent Articles
1.
Hata K, Wakamori K, Hirakawa-Yamamura A, Ichiyama-Kobayashi S, Yamaguchi M, Okuzaki D, et al.
J Cell Physiol
. 2024 Nov;
240(1):e31490.
PMID: 39568258
The growth plate is the primary site of longitudinal bone growth with chondrocytes playing a pivotal role in endochondral bone development. Chondrocytes undergo a series of differentiation steps, resulting in...
2.
Yoshida Y, Inubushi T, Yokoyama M, Nag P, Sasaki J, Oka A, et al.
Dis Model Mech
. 2024 Nov;
17(12).
PMID: 39508796
The sulfate transporter gene SLC26A2 is crucial for skeletal formation, as evidenced by its role in diastrophic dysplasia, a type of skeletal dysplasia in humans. Although SLC26A2-related chondrodysplasia also affects...
3.
Liu S, Xu L, Kashima M, Narumi R, Takahata Y, Nakamura E, et al.
Dev Dyn
. 2024 Sep;
254(3):257-271.
PMID: 39320016
Background: Embryonic craniofacial development involves several cellular and molecular events that are evolutionarily conserved among vertebrates. Vertebrate models such as mice and zebrafish have been used to investigate the molecular...
4.
Jiang Q, Nagano K, Moriishi T, Komori H, Sakane C, Matsuo Y, et al.
J Orthop Translat
. 2024 Jul;
47:161-175.
PMID: 39027344
Background: Zinc finger-containing transcription factor Osterix/Specificity protein-7 (Sp7) is an essential transcription factor for osteoblast differentiation. However, its functions in differentiated osteoblasts remain unclear and the effects of osteoblast-specific deletion...
5.
Ichiyama-Kobayashi S, Hata K, Wakamori K, Takahata Y, Murakami T, Yamanaka H, et al.
JCI Insight
. 2024 Jun;
9(11).
PMID: 38855864
The transcription factor SRY-related HMG box 9 (Sox9) is essential for chondrogenesis. Mutations in and around SOX9 cause campomelic dysplasia (CD) characterized by skeletal malformations. Although the function of Sox9...
6.
Murakami T, Ruengsinpinya L, Takahata Y, Nakaminami Y, Hata K, Nishimura R
Sci Rep
. 2023 Dec;
13(1):22778.
PMID: 38123662
Growth differentiation factor 5 (GDF5), a BMP family member, is highly expressed in the surface layer of articular cartilage. The GDF5 gene is a key risk locus for osteoarthritis and...
7.
Nishimura R
Int J Mol Sci
. 2023 Mar;
24(6).
PMID: 36982339
Recent technical and conceptual advances in molecular and cellular biology have dramatically advanced bone and cartilage biology [...].
8.
Murakami T, Takahata Y, Hata K, Ebina K, Hirose K, Ruengsinpinya L, et al.
Sci Signal
. 2022 Nov;
15(758):eabl5304.
PMID: 36318619
Proinflammatory cytokines play critical roles in the pathogenesis of joint diseases. Using a mass spectrometry-based cloning approach, we identified Semaphorin 4D (Sema4D) as an inflammatory cytokine that directly promoted cartilage...
9.
Inubushi T, Nakanishi Y, Abe M, Takahata Y, Nishimura R, Kurosaka H, et al.
PLoS Genet
. 2022 Jul;
18(7):e1009765.
PMID: 35839257
Hyaluronan (HA) is a major extracellular matrix component whose tissue levels are dynamically regulated during embryonic development. Although the synthesis of HA has been shown to exert a substantial influence...
10.
Yagi H, Takahata Y, Murakami T, Nakaminami Y, Hagino H, Yamamoto S, et al.
J Bone Miner Metab
. 2022 Jun;
40(5):723-734.
PMID: 35763224
Introduction: Osteoarthritis is a common joint disease that causes destruction of articular cartilage and severe inflammation surrounding knee and hip joints. However, to date, effective therapeutic reagents for osteoarthritis have...