Michael Hagemann-Jensen
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Explore the profile of Michael Hagemann-Jensen including associated specialties, affiliations and a list of published articles.
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985
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Recent Articles
1.
Grommisch D, Lund H, Eenjes E, Julien A, Goritz C, Harris R, et al.
Dev Cell
. 2024 Oct;
60(2):320-336.e9.
PMID: 39426382
Regionalized disease prevalence is a common feature of the gastrointestinal tract. Herein, we employed regionally resolved Smart-seq3 single-cell sequencing, generating a comprehensive cell atlas of the adult mouse esophagus. Characterizing...
2.
Russell S, Zhao C, Biondic S, Menezes K, Hagemann-Jensen M, Librach C, et al.
Nat Commun
. 2024 Oct;
15(1):8634.
PMID: 39367016
Understanding the molecular circuitries that govern early embryogenesis is important, yet our knowledge of these in human preimplantation development remains limited. Small non-coding RNAs (sncRNAs) can regulate gene expression and...
3.
Noble J, Lentini A, Hagemann-Jensen M, Sandberg R, Reinius B
Nat Commun
. 2024 Sep;
15(1):8373.
PMID: 39333520
Single-cell RNA-sequencing (scRNAseq) is revolutionizing biomedicine, propelled by advances in methodology, ease of use, and cost reduction of library preparation. Over the past decade, there have been remarkable technical improvements...
4.
Fait B, Cotto B, Murakami T, Hagemann-Jensen M, Zhan H, Freivald C, et al.
bioRxiv
. 2024 Sep;
PMID: 39314356
The spinal cord receives inputs from the cortex via corticospinal neurons (CSNs). While predominantly a contralateral projection, a less-investigated minority of its axons terminate in the ipsilateral spinal cord. We...
5.
Ramskold D, Hendriks G, Larsson A, Mayr J, Ziegenhain C, Hagemann-Jensen M, et al.
Nat Cell Biol
. 2024 Aug;
26(10):1725-1733.
PMID: 39198695
Analyses of transcriptional bursting from single-cell RNA-sequencing data have revealed patterns of variation and regulation in the kinetic parameters that could be inferred. Here we profiled newly transcribed (4-thiouridine-labelled) RNA...
6.
Carrelha J, Mazzi S, Winroth A, Hagemann-Jensen M, Ziegenhain C, Hogstrand K, et al.
Nat Immunol
. 2024 May;
25(6):1007-1019.
PMID: 38816617
Rare multipotent stem cells replenish millions of blood cells per second through a time-consuming process, passing through multiple stages of increasingly lineage-restricted progenitors. Although insults to the blood-forming system highlight...
7.
Mold J, Weissman M, Ratz M, Hagemann-Jensen M, Hard J, Eriksson C, et al.
Cell Syst
. 2024 Feb;
15(2):149-165.e10.
PMID: 38340731
Cell types can be classified according to shared patterns of transcription. Non-genetic variability among individual cells of the same type has been ascribed to stochastic transcriptional bursting and transient cell...
8.
Engblom C, Thrane K, Lin Q, Andersson A, Toosi H, Chen X, et al.
Science
. 2023 Dec;
382(6675):eadf8486.
PMID: 38060664
The spatial distribution of lymphocyte clones within tissues is critical to their development, selection, and expansion. We have developed spatial transcriptomics of variable, diversity, and joining (VDJ) sequences (Spatial VDJ),...
9.
Moura P, Mortera-Blanco T, Hofman I, Todisco G, Kretzschmar W, Bjorklund A, et al.
Cancer Res
. 2023 Nov;
84(2):211-225.
PMID: 37921711
Significance: Ring sideroblast isolation combined with state-of-the-art multiomics identifies survival mechanisms underlying SF3B1-mutant erythropoiesis and establishes an active role for erythroid differentiation and ring sideroblasts themselves in SF3B1-mutant myelodysplastic syndrome...
10.
Klose D, Needhamsen M, Ringh M, Hagemann-Jensen M, Jagodic M, Kular L
Mult Scler Relat Disord
. 2023 Sep;
79:104991.
PMID: 37708820
Background: A compelling body of evidence implicates cigarette smoking and lung inflammation in Multiple Sclerosis (MS) susceptibility and progression. Previous studies have reported epigenetic age (DNAm age) acceleration in blood...