Richard W Gelling
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Explore the profile of Richard W Gelling including associated specialties, affiliations and a list of published articles.
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19
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784
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Recent Articles
1.
Larger E, Wewer Albrechtsen N, Hansen L, Gelling R, Capeau J, Deacon C, et al.
Endocrinol Diabetes Metab Case Rep
. 2016 Dec;
2016.
PMID: 27933176
Learning Points: Loss of function of the glucagon receptor may not necessarily lead to the dysregulation of glucose homeostasis.Loss of function of the glucagon receptor causes hyperaminoacidemia, hyperglucagonemia and α-cell...
2.
Zheng Z, Gelling R
J Diet Suppl
. 2016 Jul;
14(2):121-131.
PMID: 27471884
Advanced liver disease (ALD) is often characterized with overt malnutrition and liver fibrosis. In this study, a dietary supplement (DS) was first developed, including branch chain amino acids, fat soluble...
3.
Shreeram S, Johns P, Subramaniam S, Ramesh S, Vaidyanathan V, Puthan J, et al.
J Nutr
. 2014 Aug;
144(10):1549-55.
PMID: 25143371
Background: β-Hydroxy-β-methylbutyrate (HMB) supplementation has been demonstrated to enhance muscle protein synthesis and attenuate loss of muscle mass by multiple pathways. The beneficial effects of HMB have been studied by...
4.
Chuah A, Jacob B, Jie Z, Ramesh S, Mandal S, Puthan J, et al.
Food Chem
. 2014 Mar;
156:227-33.
PMID: 24629962
Curcumin has been shown to have a wide variety of biological activities for various human diseases including inflammation, diabetes and cancer. However, the poor oral bioavailability of curcumin poses a...
5.
Ouhilal S, Vuguin P, Cui L, Du X, Gelling R, Reznik S, et al.
Am J Physiol Endocrinol Metab
. 2011 Dec;
302(5):E522-31.
PMID: 22167521
Alterations in insulin signaling as well as insulin action predispose to infertility as well as adverse pregnancy outcomes; however, little is known about the role of glucagon signaling in reproduction....
6.
Baskin D, Kim F, Gelling R, Russell B, Schwartz M, Morton G, et al.
Endocrinology
. 2010 Jul;
151(9):4207-13.
PMID: 20610562
Evidence suggests that release of oxytocin in the nucleus tractus solitarius (NTS) of the hindbrain from descending projections that originate in the paraventricular nucleus can inhibit food intake by amplifying...
7.
Roohk D, Varady K, Turner S, Emson C, Gelling R, Shankaran M, et al.
J Pharmacol Exp Ther
. 2010 Jan;
333(1):281-9.
PMID: 20065017
Glucocorticoids are widely prescribed to treat autoimmune and inflammatory diseases. Although they are extremely potent, their utility in clinical practice is limited by a variety of adverse side effects. Development...
8.
Gelling R, Vuguin P, Du X, Cui L, Romer J, Pederson R, et al.
Am J Physiol Endocrinol Metab
. 2009 Jul;
297(3):E695-707.
PMID: 19602585
In addition to its primary role in regulating glucose production from the liver, glucagon has many other actions, reflected by the wide tissue distribution of the glucagon receptor (Gcgr). To...
9.
Gelling R, Yan W, Al-Noori S, Pardini A, Morton G, Ogimoto K, et al.
Endocrinology
. 2008 Aug;
149(12):6053-64.
PMID: 18687778
Energy homeostasis involves central nervous system integration of afferent inputs that coordinately regulate food intake and energy expenditure. Here, we report that adult homozygous TNFalpha converting enzyme (TACE)-deficient mice exhibit...
10.
Sorensen H, Winzell M, Brand C, Fosgerau K, Gelling R, Nishimura E, et al.
Diabetes
. 2006 Nov;
55(12):3463-9.
PMID: 17130493
In previous studies, glucagon receptor knockout mice (Gcgr(-/-)) display reduced blood glucose and increased glucose tolerance, with hyperglucagonemia and increased levels of glucagon-like peptide (GLP)-1. However, the role of glucagon...