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Christopher D Morrison

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Recent Articles
1.
Soto P, Young M, Nguyen S, Federoff M, Goodson M, Morrison C, et al.
Pharmacol Biochem Behav . 2024 Dec; 247():173951. PMID: 39722423
The use of second-generation antipsychotic (SGA) medications in pediatric patients raises concerns about potential long-term adverse outcomes. The current study evaluated the long-term effects of treatment with risperidone or olanzapine...
2.
Francois M, Kaiser L, He Y, Xu Y, Salbaum J, Yu S, et al.
Metabolism . 2024 Dec; 163:156100. PMID: 39672257
The dorsomedial hypothalamus (DMH) receives inputs from the preoptic area (POA), where ambient temperature mediates physiological adaptations of energy expenditure and food intake. Warm-activated POA neurons suppress energy expenditure via...
3.
Khan M, Kim S, Ross R, Corpodean F, Spann R, Albarado D, et al.
Mol Metab . 2024 Nov; 91:102068. PMID: 39571902
Objective: Dietary protein restriction induces adaptive changes in food preference, increasing protein consumption over carbohydrates or fat. We investigated whether motivation and reward signaling underpin these preferences. Methods And Results:...
4.
Munzberg H, Heymsfield S, Berthoud H, Morrison C
Metabolism . 2024 Sep; 161:156026. PMID: 39245434
The cloning of leptin 30 years ago in 1994 was an important milestone in obesity research. Prior to the discovery of leptin, obesity was stigmatized as a condition caused by...
5.
Khan M, Kim S, Ross R, Corpodean F, Spann R, Albarado D, et al.
bioRxiv . 2024 May; PMID: 38798313
Dietary protein restriction induces adaptive changes in food preference, increasing protein consumption over carbohydrates or fat. We investigated whether motivation and reward signaling underpin these preferences. In an operant task,...
6.
Kim S, Spann R, Khan M, Berthoud H, Munzberg H, Albaugh V, et al.
Neuropharmacology . 2024 May; 255:110010. PMID: 38797244
Free-feeding animals navigate complex nutritional landscapes in which food availability, cost, and nutritional value can vary markedly. Animals have thus developed neural mechanisms that enable the detection of nutrient restriction,...
7.
Berthoud H, Munzberg H, Morrison C, Neuhuber W
Auton Neurosci . 2024 Apr; 253:103174. PMID: 38579493
The liver is a large organ with crucial functions in metabolism and immune defense, as well as blood homeostasis and detoxification, and it is clearly in bidirectional communication with the...
8.
Shah H, Kramer A, Mullins C, Mattern M, Gannaban R, Townsend R, et al.
Nutrients . 2023 Apr; 15(7. PMID: 37049555
Type 2 diabetes (T2D) is a challenging health concern worldwide. A lifestyle intervention to treat T2D is difficult to adhere, and the effectiveness of approved medications such as metformin, thiazolidinediones...
9.
Ross R, He Y, Townsend R, Schauer P, Berthoud H, Morrison C, et al.
Am Surg . 2023 Mar; 89(8):3600-3602. PMID: 36867071
Background: Obesity contributes significant disease burden worldwide, including diabetes, cardiovascular disease, and cancer. While bariatric surgery is the most effective and durable obesity treatment, the mechanisms underlying its effects remain...
10.
Albaugh V, He Y, Munzberg H, Morrison C, Yu S, Berthoud H
Mol Metab . 2022 Jun; 68():101517. PMID: 35644477
Background: Bariatric or weight loss surgery is currently the most effective treatment for obesity and metabolic disease. Unlike dieting and pharmacology, its beneficial effects are sustained over decades in most...